多层螺旋CT灌注成像对重症急性胰腺炎的临床应用研究  

The study of perfusion imaging in severe acute pancreatitis with multislice spiral CT

作　　者：征锦[1,2] 邵娟[1,2] 施斌斌[1,2] 叶靖[1,2] 

机构地区：[1]扬州大学临床医学院 [2]江苏省苏北人民医院影像科

出　　处：《医学影像学杂志》2010年第1期80-82,共3页Journal of Medical Imaging

基　　金：扬州市社会发展人口健康类科技专项计划项目YZS2007006

摘　　要：目的:探讨多层螺旋CT灌注成像对重症急性胰腺炎的诊断价值。方法:使用16排螺旋CT对9例重症急性胰腺炎患者(SAP)和17例轻症急性胰腺炎(MAP)以及41例正常胰腺组进行CT灌注扫描。应用perfusion3软件包进行数据处理,计算各组的血流量(BF)、血容量(BV)、平均通过时间(MTT)、毛细血管通透性(PS)等灌注参数,对各组样本灌注数据的均数及标准差进行单因素方差分析。对急性胰腺炎临床生化指标与灌注参数BF变量之间进行相关性检验。结果:MAP、SAP的BF、BV平均值较正常胰腺组显著降低(P<0.01),PS高于正常组(P<0.05),MAP组的BF、BV显著高于SAP组。结论:CT灌注成像技术对急性胰腺炎的诊断和指导临床治疗具有重要意义。Objective： To evaluate the characteristics of the CT perfusion for severe acute pancreatitis. Methods： We performed CT perfusion scan on three groups ofg, 17 and 41 cases with severe, mild and normal pancreatitis respectively, using 16 rows spiral CT, and got the perfusion data of the relevant groups including blood flow （BL）, blood volume（BV）, mean transit time（MTT）, capillary perme- ability（PS） with perfusion package 3. We analize the data deviation between the groups mentioned above. Furthmore, we still adapt correlation test to compare the clinical biochemical indicators of MAP and SAP, with the variance BF. Results：The mean values of BF, BV reduce signiilcaUy in the groups of MAP, SAP compared to the normal group （ P 〈 0.01）, only PS goes higher than that of the normal group （ P 〈 0.05）. At the same time, they are obviously higher in MAP group than in SAP group. Conclusion：CT peffusion techniques are of great significance in early diagnosis in SAP, and in guiding the clinical therapy.

关 键 词：急性胰腺炎 灌注成像 体层射影术 X线计算机 

分 类 号：R576[医药卫生—消化系统] R814.42[医药卫生—内科学]