难治性胃食管反流病  

Refractory Gastroesophageal Reflux Disease

作　　者：陈鸣艳[1] 吕宾[1] 

机构地区：[1]浙江中医药大学附属第一医院消化科

出　　处：《胃肠病学》2010年第1期57-59,共3页Chinese Journal of Gastroenterology

摘　　要：近年来，有学者发现部分胃食管反流病（GERD）患者对质子泵抑制剂（PPI）治疗无效，由此提出了“难治性GERD”的概念。通过对难治性GERD病例进行研究，已发现部分GERD相关病理生理机制，并在此基础上提出了一些新的检测技术和治疗方法，以使这部分患者的症状能有所改善。本文就难治性GERD的研究现状作一概述。Part of the patients with gastroesophageal reflux disease （GERD） have sustained symptoms despite treated with proton pump inhibitors （PPI）. For this reason, a new concept of ＂refractory GERD＂ was raised. Study on refractory GERD patients illuminated some of the underlying pathophysiological mechanisms. Based on these results, some valuable detective techniques and treatment modalities have been developed, which may ameliorate the symptoms of patients with refractory GERD. This article is a review of current study on refractory GERD.

关 键 词：胃食管反流 质子泵 诊断 治疗 

分 类 号：R571[医药卫生—消化系统]