西酞普兰与米安舍林治疗老年抑郁症的对照研究  

Comparative study of Ciralopram and Mianserin in the treatment of depression

作　　者：贾金鼎[1] 郭平[1] 

机构地区：[1]河南省驻马店市精神病医院,463000

出　　处：《中国实用医药》2010年第2期41-42,共2页China Practical Medicine

摘　　要：目的比较西酞普兰与米安舍林治疗老年抑郁症的疗效及安全性。方法选择符合入组条件的78例抑郁症患者,随机分为两组,分别给予西酞普兰与米安舍林治疗,疗程8周,采用汉密尔顿抑郁量表(HAMD)及汉密尔顿焦虑量表(HAMA)在治疗前及治疗的2、4、6、8周评定药物疗效;用副反应量表(TESS)评定不良反应。结果西酞普兰组与米安舍林组总体疗效相当,疗后HAMD和HAMA总分均有显著减少,西酞普兰组起效快,不良反应轻,安全性好。结论西酞普兰治疗老年抑郁症安全有效,并且起效快,不良反应轻。Objective To explore clinical efficacy and safely of Citalopram and Mianserin in the treatment of depression. Methods Sixty eight patients with depression were treated randomly with Citalopram or Mianserin for six weeks, and measured with Hamilton depressive Scale （HAMD） , Hamilton anxiety Scale （ HAMA） and treatment emergent Symptom Scale （TESS） before treatment and,2,4,6,8 weeks after treatment. Resuits The both drugs were similar in efficacy. The side effects of both were less. Conclusions Citalopram and Mianserin are both effective and safe antidepressants.

关 键 词：西酞普兰 米安舍林 老年抑郁症 

分 类 号：R749.4[医药卫生—神经病学与精神病学] R971.43[医药卫生—临床医学]