奥美拉唑、伊托必利和铝镁加联合治疗反流性食管炎的疗效观察  

Combination of Omeprazole,Itopride and Almagate for Reflux Esophagitis

作　　者：施荣杰[1] 杨理伟[1] 吴泽生[1] 何昉[1] 

机构地区：[1]大理学院附属医院内二科,云南大理671000

出　　处：《中国现代医生》2010年第3期155-156,共2页China Modern Doctor

摘　　要：目的探讨奥美拉唑、伊托必利和铝镁加联合治疗反流性食管炎的临床疗效。方法将53例反流性食管炎患者随机分为对照组(26例)和观察组(27例),对照组予口服奥美拉唑、伊托必利等综合治疗,观察组在对照组综合治疗的基础上加服铝镁加混悬液15mL,3次/d,于治疗8周后复查胃镜,观察镜下治愈率。结果对照组内镜下治愈率为65.4%,观察组内镜下治愈率为92.6%,两组比较有统计学意义(P<0.05)。结论在口服奥美拉唑、伊托必利等综合治疗的基础上,加服铝镁加能提高反流性食管炎的治疗效果。Objective To evaluate the effects of Omeprazole combined with hopride and Almagate in the treatment of reflux esophagitis. Methods Fifty-three cases of reflux exsophagitis were randomly divided into two groups：observation group （n=27）and control group（n=26）. Both groups were given Omeprazole and Itopride,and Almagate suspension was added to the observation group（n=27）15ml（3 times a day）, and at the end of 8-week treatment, the curative rate was rechecked by endoscope. Results The curative rate under endoscope was 65.4% in the control group and 92.6% in the observation group,respectively,and the difference between the two groups was significant（P〈0.05）. Conclusion Omeprazole combined with hopride and Almagate can effectively improve the curative effect in the treatment of reflux esophagitis.

关 键 词：反流性食管炎 胃食管反流病 奥美拉唑 伊托必利 铝镁加 

分 类 号：R571[医药卫生—消化系统]