偏执型与非偏执型精神分裂症患者的发病特征及相关因素比较  

Paranoid and non-paranoid schizophrenic inpatients' disease characteristics and related factors

作　　者：孟祥飞[1] 史杰萍[1] 寇长贵[1] 俞琼[1] 陶然[2] 于雅琴[1] 桑红[3] 

机构地区：[1]吉林大学公共卫生学院流行病与卫生统计学教研室、医学基因组中心,吉林长春130021 [2]江苏省疾病预防控制中心,江苏南京210009 [3]长春市心理医院,吉林长春130021

出　　处：《中华疾病控制杂志》2010年第1期18-20,共3页Chinese Journal of Disease Control & Prevention

基　　金：国家自然科学基金(30671808)

摘　　要：目的探讨偏执型与非偏执型精神分裂症患者的发病特征及其相关因素。方法采用自行设计的调查问卷,以中国精神障碍分类诊断标准第2版修订本收集1996-2005年住院精神分裂症患者的病历2801份,应用SPSS12.0统计软件进行数据的录入、管理及统计分析。结果女性多于男性,男女比为0.87:1,男性较女性早发(P<0.001),非偏执型患者中女性多于男性(P<0.001);非偏执型患者首次发病年龄早于偏执型(P<0.001);偏执型患者中城镇人口、老年、已婚、高等教育、阳性家族史和伴发躯体疾病的所占比重大(P<0.05);而非偏执型患者多由诱因起病(P<0.001);两组在病前人格和出生季节上的分布差异无统计学意义(P>0.05)。结论不同亚型的精神分裂症患者具有不同的发病特征和疾病相关因素,应采取有针对性的预防和治疗措施来降低和减缓疾病的发生、发展。Objective To investigate the diseases characteristics and related factors among paranoid and non-paranoid schizophrenic inpatients. Methods A total of 2 801 clinical records of schizophrenic inpatients classified as paranoid and non-paranoid according to C/2MD-Ⅱ-R was collected by self-designed questionnaire. Results The number of female patients was more than male patients, and the male to female ratio was 0.87：1. Male had earlier onset age than female （P〈0. 001）. Female had greatly percentage in non-paranoid inpatients （P〈 0. 001）; the non-paranoid inpatients had earlier onset age than paranoid inpatients （ P 〈 0. 001 ） ; compare had to non-paranoid patients, paranoid patients had more people who live in city/town, have a marriage, higher education, older age, positive family history, body diseases （P 〈 0.05）, while non-paranoid inpatients are more likely to have causes （P〈 0. 001 ）; there were no significantly different distributions of personality and birth season between two groups （P〉0.05）. Conclusions Paranoid and non-paranoid schizophrenic inpatients have different disease characteristics and related factors. More specific measurements of prevention and treatment for decreasing occurrence of this disease are needed.

关 键 词：精神分裂症 住院患者 偏执型 病因 

分 类 号：R749.3[医药卫生—神经病学与精神病学]