幽门螺杆菌感染合理用药干预项目研究  

Study of intervention of rational drug use on Helicobacter pylori infection

作　　者：陈德成[1] 孔少珊[1] 王丽[1] 

机构地区：[1]广东省珠海市妇幼保健院药剂科,519000

出　　处：《中国医药》2010年第2期172-173,共2页China Medicine

摘　　要：目的对我院内科根治幽门螺杆菌感染的用药情况进行调查，评价干预措施对我院医生用药行为的影响。方法按照合理用药干预计划研究模式，选择我院2007年3月至2008年10月诊断为消化性溃疡、胃炎及幽门螺杆菌感染阳性患者的处方1200张进行分析研究分4个阶段，每阶段调查300份。结果干预后实施诊断性试验的比例由51．0％（153／300）升至91．0％（273／300），遵循指南用药比例由59．0％（177／300）提高到80．0％（240／300），药物治疗疗程符合治疗规范的处方比例由50．0％（150／300）提高到81．0％（243／300），幽门螺杆菌感染治愈率由61．7％（185／300）上升到88．0％（264／300）。结论实施有效可行的干预措施能够促进药物的合理使用，规范医生的用药行为。Objective To investigate the usage of Helicobacter pylori （Hp）eradication and to evaluate the influence of the intervention of the clinical prescription behavior. Methods MTP were introduced andl200 prescriptions for peptic ulcer, chronic gastritis and HP-positive patients were randomly selected from March 2007 to Oc- tober 2008. Result After MTP Intervention,the proportion of diagnostic tests application increased from 51.0% to 91.0%. Rational drug use increased from 59.0% to 80.0%. Rational course of treatment increased from 50.0% to 81.0% and the cure rate increased from 61.7% to 88.0%. Conclusion Effective intervention promotes the rational drug use and standardizes clinical prescription behavior.

关 键 词：幽门螺杆菌 合理用药 干预 

分 类 号：R573.1[医药卫生—消化系统]