CT动脉单期与MR双动脉期诊断肝细胞癌对比分析  

Comparison of single-arterial phase enhancement CT and dual-arterial phase of enhancement MR for the detection of hepatocellular carcinoma

作　　者：邢古生[1] 王爽[1] 欧阳汉[1] 马霄虹[1] 周纯武[1] 

机构地区：[1]中国医学科学院北京协和医学院肿瘤医院影像诊断科,北京100021

出　　处：《中国介入影像与治疗学》2010年第1期1-4,共4页Chinese Journal of Interventional Imaging and Therapy

基　　金："十一五"国家科技及支撑课题(2007BAI05B05)

摘　　要：目的以螺旋CT、3．0TMR对肝细胞癌（HCC）患者行增强扫描，对比CT单动脉期与MR双动脉期扫描对HCC病灶的显示能力。方法39例HCC患者59个病灶纳入本研究，并完成CT及MR检查。根据病灶大小，分为〉3cm组（n=20）、1～3cm组（n=27）及〈1cm组（n=12）。CT单动脉期采用25S延迟扫描；MR双动脉期采用肝脏加速容积采集（LAVA）技术，延迟时间分别相当于第17秒和24秒。比较CT动脉期和MR双动脉期对HCC病灶的显示能力。结果CT动脉期和MR双动脉期对小于〈1cm组HCC病灶的敏感度分别为50．00％（6／12）和75．00％（9／12），MR双动脉期的敏感度显著高于CT动脉期（P=0．04）；在1～3cm组，CT动脉期与MR双动脉期的敏感度分别为66．67％（18／27）、81．48％（22／27）（P〉0．05）；在〉3cm组，CT动脉期与MR双动脉期的敏感度均为95．00％（19／20）。结论对小于1cm的HCC灶，MR双动脉期扫描对病灶的检出效能高于CT单动脉期扫描。Objective To evaluate the detectability of dual-arterial phase of MRI and single-artery phase of CT scan for hepatocellular carcinoma （HCC）. Methods A total of 39 patients with HCC underwent CT and MR scan, and 59 lesions of HCC were confirmed definitely. According to lesion size, the lesions were divided into 3 groups： 〉3 cm group （n= 20）, 1--3 cm group （n=27） and 〈1 cm group （n=12）. CT was performed with 25 seconds delaying for artery phase. MR imaging was performed with liver accelerate volume acquisition （LAVA） technique, dual-artery phases included early artery phase of 17 seconds delaying and a mid-artery phase of 24 seconds delaying. The detectability of dual-artery phase of MR was compared with that of single-artery phase of CT. Results In 〈1 cm group, the sensitivity of CT single-artery phase images and MR dual-artery phase images in detecting HCC lesions was 50.00% （6/12） and 75.00% （9/12）, respectively; the later showed a higher sensitivity （P=0. 04）. In groups of 1-3 cm and 〉3 cm, the sensitivity of the two technique had no statistical difference （66.67% vs 81.48% and 95.00% vs 95.00%）. Conclusion For the detection of 〈1 cm HCC, dual-artery phase MRI has higher detectability than single artery phase enhancement CT.

关 键 词：肝肿瘤 体层摄影术 X线计算机 磁共振成像 诊断显像 

分 类 号：R735.7[医药卫生—肿瘤] R814.42[医药卫生—临床医学]