最近5年福建省细菌性肝脓肿的致病菌及伴发疾病变化  

Study on the change of pathogenic bacteria and concomitant disease of pyogenic liver abscess in recent 5 years of Fujian province

作　　者：周阿佩[1] 彭孝纬[1] 

机构地区：[1]福建医科大学福建省立医院消化研究所,福建福州350001

出　　处：《胃肠病学和肝病学杂志》2010年第2期170-173,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的研究近5年福建省细菌性肝脓肿的致病菌及与伴发疾病之间的关系,并与10年前病例比较,了解细菌性肝脓肿致病菌及伴发疾病的变化状况。方法回顾性分析最近5年(2004年1月～2008年6月)收住我院的细菌性肝脓肿病例的临床资料(A组),并与1994年1月～1998年12月期间的肝脓肿病例(B组)比较,调查两组病例的致病菌培养结果,并进行统计学分析及对比。结果A组病例中胆系疾病与糖尿病的构成比分别占17.46%、30.95%,而B组中二者的构成比分别占32.35%、16.18%。A组病例培养结果以肺炎克雷伯杆菌所占比例最大;而B组以大肠埃希菌所占比例最大。结论最近5年福建省细菌性肝脓肿的伴发疾病中胆系疾病比例下降,而糖尿病的比例升高,主要致病菌由大肠埃希菌转变为肺炎克雷伯杆菌。Objective To analyze the relationship between the pathogenic bacteria and the concomitant diseases of pyogenic liver abscess in recent 5 years of Fujian province,and to find the changes of the pathogenic bacteria and the concomitant diseases of pyogenic liver abscess by comparing these cases to those in 10 years ago.Methods The clinical features of pyogenic liver abscess patients admitted in our hospital from January 2004 to June 2008（for group A） were analyzed retrospectively,and the clinical data were compared to patients with pyogenic liver abscess admitted from January 1994 to December 1998（for group B）.The outcome of bacterial cultures of these patients were investigated.Then the difference between the two groups was compared by statistical analysis.Results In group A,patients with biliary disease and diabetes mellitus took proportion were 17.46% and 30.95% respectively,while in group B,the proportions were 32.35% and 16.18%.Klebsiella pneumoniae was the dominant bacteria in group A while E.coli was the most important bacteria in group B.Conclusion The concomitant disease of biliary disease has declined and diabetes mellitus has ascended.And the major pathogenic bacteria of E.coli has been taken place by Klebsiella pneumoniae in recent 5 years of Fujian province.

关 键 词：细菌性肝脓肿 伴发疾病 致病菌 

分 类 号：R575.4[医药卫生—消化系统]