代谢综合征与非酒精性脂肪肝的关系研究  

Relationship between metabolic syndrome and non-alcoholic fatty liver disease

作　　者：胡晓春[1] 包国豪[1] 陈法东[1] 

机构地区：[1]温州医学院附属第三医院,浙江瑞安325200

出　　处：《现代实用医学》2010年第1期7-8,11,共3页Modern Practical Medicine

基　　金：温州市科技计划项目资助项目;编号:Y20080057

摘　　要：目的探讨代谢综合征(MS)和非酒精性脂肪肝(NAFLD)的关系。方法对2351例健康体检职工的MS流行情况进行调查,并分析其影响因素。结果2351例中,MS检出率为11.0%,MS组中脂肪肝的检出率显著高于非MS组(P<0.01)。NAFLD组中MS、肥胖、高血压、血脂代谢异常、糖代谢异常的检出率显著高于非NAFLD组(P<0.01)。回归分析显示,MS与NAFLD、体质量指数、甘油三酯、高密度脂蛋白胆固醇、高血压及血糖有密切关系。结论MS与NAFLD的关系密切,NAFLD患者具有MS的各种组分聚集的特征,NAFLD是MS的重要危险因素之一。Objective To explore the relationship between metabolic syndrome （MS） and non-alcoholic fatty liver disease （NAFLD）. Methods The prevalence of MS and the related risk factors of MS among 2351 persons in a medical examination were analysed. Results The prevalence of MS was 11.0%. The prevalence of NAFLD in MS group was significantly higher than that of non-MS group. The prevalences of MS, obesity, hypertension, dyslipidemia, glucose metabolic abnormality in NAFLD group were significantly higher than those of non-NAFLD group（P〈0.01）. Logistic regression analysis showed that there was significant correlation between NAFLD, BMI, TG, HDL-C, hypertension and MS. It indicated that NAFLD,obesity, lipid metabolism disorder and hypertension were the risk factors of MS. Conclusion There is a close relation between MS and NAFLD. NAFLD is one of the most important risk factor of MS.

关 键 词：代谢综合征 脂肪肝 非酒精性 危险因素 

分 类 号：R575.5[医药卫生—消化系统]