宫颈癌急性放射性肠炎近期疗效观察  

THE SHORT TERM EFFECTS OF 654-2 ON ACUTE RADIATION ENTERITIS IN CERVICAL CANCER

作　　者：向莉[1] 杨红茹[1] 吴敬波[1] 叶华[1] 张艳玲[1] 

机构地区：[1]泸州医学院附属医院肿瘤科,四川泸州646000

出　　处：《泸州医学院学报》2010年第1期50-52,共3页Journal of Luzhou Medical College

摘　　要：目的:临床研究654-2治疗宫颈癌急性放射性肠炎的疗效。方法:收集我科2004年1月至2006年9月宫颈癌放疗患者共53例,将患者分为2组,研究组27例,对照组26例。研究组:654-25mg,每日3次,同时口服次碳酸铋0.9,每日3次;对照组:仅口服次碳酸铋0.9,每日3次,治疗1周为1疗程。结果:治疗腹泻研究组有效率为92.59%;对照组有效率为61.54%。两组腹痛缓解情况:研究组缓解率为96.30%;对照组缓解率为34.52%。两组间疗效比较差异有统计学意义(P<0.05)。结论:本研究发现654-2及次碳酸铋联合应用于宫颈癌急性放射性肠炎的治疗有较好的疗效,且未见严重不良反应。Objective： Clinical research of therapeutic effct of 654-2 in treatment of acute radiation enteritis in cervical cancer. Methods：53 cases of cervix carcinoma received radiotherapy from 2004.01 to 2006.09 were divided into two groups：study group,27 cases,took 5mg of 654-2 with 0.9 of bismuth sub-carbonate three times a day orally;control group ,26 cases,took 0.9 of bismuth sub-carbonate three times a day for one week.Results： The effective rate of study group and control group was 92.59%,and 61.54% respectively, the difference was significant （P〈0.05）.The abdominal pain relief rates were 96.30% and 34.52% respectively, the difference was significant （P〈 0.05）.Conclusion： 654-2 with bismuth has good effect on acute radiation enteritis in cervical cancer,with no serious adverse events.

关 键 词：654-2 次碳酸铋 宫颈癌 放射性肠炎 

分 类 号：R737.33[医药卫生—肿瘤]