微波诱导PTSA催化酯化合成没食子酸正丁酯  

Synthesis of n Butyl Gallate in Catalysis of p Methyl Toluenesulfonic Acid Induced by Microwaves

作　　者：苑克国[1,2] 樊兴君[1,2] 李楠 谭干祖[1,2] 焦天权 

机构地区：[1]中国科学院兰州化学物理研究所 [2]兰州大学化学系

出　　处：《精细化工》1998年第5期8-9,共2页Fine Chemicals

摘　　要：采用微波辐射技术，以对甲苯磺酸（ＰＴＳＡ）作催化剂，没食子酸和正丁醇直接酯化合成没食子酸正丁酯。最佳反应条件为：没食子酸１９．３ｍｍｏｌ，催化剂０．５ｇ，二者的摩尔比是１∶０１３５，正丁醇２０ｍｌ，微波功率５２５Ｗ，辐射时间２０ｍｉｎ，酯化产率为８７９％。该条件下的反应速度是酶促反应速度的５４倍。The n butyl gallate was synthesized by esterification of butyl alcohol and gallic acid in catalysis of p methyl toluenesulfonic acid (PTSA) induced by microwaves.The optimum reaction conditions were as follows:gallic acid and PTSA were 19.3mmol and 0.5g,i.e.the molar ratio of gallic acid to catalyst was 1∶0.135,the quantities of n butyl alcohol,microwave power,and microwave irradiation time were 20ml,525W,and 20min respectively.The yield of n butyl gallate was 87.9%.The rate of reaction was up to 53 times faster in catalysis of PTSA under microwaves than by enzymatic method.

关 键 词：没食子酸正丁酯 微波 酯化 PTSA 

分 类 号：TQ245.4[化学工程—有机化工]