National Science Foundation of China(51172111,51402159);Innovation Project of China Electronics Technology Group Corporation No.46 Research Institute(CJ20140401)
The synthesis of novel isoxazolo[2,3-c][1,3,5]thiadiazepin-2-ones has been achieved in excellent yields by one-pot three-component Domino reaction without the production of toxic waste products by using p-toluene sulf...