丝裂霉素C在LASIK术后外伤致角膜上皮植入患者手术治疗中的应用  

Application of mitomycin C in surgical treatment of epithelial ingrowth after LASIK with trauma

作　　者：陈静[1] 韩苏宁[1] 邓金印[1] 

机构地区：[1]广州军区广州总医院眼科,广东广州510010

出　　处：《眼外伤职业眼病杂志》2010年第2期101-103,共3页Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries

摘　　要：目的探讨丝裂霉素C(MMC)在准分子激光原位角膜磨镶术(LASIK)术后外伤致角膜上皮植入患者的手术治疗中应用的临床疗效。方法在LASIK术后外伤致角膜上皮植入21例(21眼)手术治疗中应用0.02%MMC,观察术后裸眼视力及角膜瓣愈合情况。结果术后裸眼视力平均为0.82±0.26,较术前明显提高(P<0.05)。绝大部分患眼角膜瓣愈合良好,3眼角膜瓣边缘部分融解,但中心视力无明显影响。结论在LASIK术后外伤致角膜上皮植入手术治疗中应用0.02%MMC可以取得良好的临床疗效。Objective To observe the clinical effect of using mitomycin C(MMC) during surgical treatment of epithelial ingrowth after laser in situ keratomileusis(LASIK) with trauma. Methods 0.02% MMC was applied in surgical treatment of epithelial ingrowth after LASIK with trauma on 21 patients(21 eyes).The uncorrected visual acuity and the recovery of corneal flap were observed after surgery. Results The uncorrected visual acuity increased after surgery (P<0.05).It was 0.82±0.26 postoperatively.Great majority of corneal flap recovered well.Fringe of the flap melted in 3 eyes,but the central visual acuity had no effect. Conclusion Excellent outcome was observed found in the surgical treatment of epithelial ingrowth after LASIK with trauma by using 0.02% MMC.

关 键 词：准分子激光原位角膜磨镶术 外伤 上皮植入 丝裂霉素C 

分 类 号：R779.63[医药卫生—眼科]