心境障碍住院患者不同年代诊断类型与处方模式研究  

Diagnosis of mood disorder inpatients in different age types and prescription pattern studies

作　　者：徐琳[1,2] 谭小林[2] 肖晓杨[2] 陈黎明[2] 赵科[2] 

机构地区：[1]重庆市医学会,400020 [2]重庆市精神卫生中心

出　　处：《重庆医学》2010年第3期275-277,共3页Chongqing medicine

摘　　要：目的了解不同年代心境障碍住院患者的诊断类型及处方模式变化情况,为临床合理用药提供参考。方法将入住重庆市精神卫生中心诊断为心境障碍患者分为2002年组(过去组)及2007年组(现在组),采用CCMD-3进行再诊断,并对两组患者的诊断亚型及用药情况进行统计与归类分析。结果现在组单相躁狂及复发性抑郁的诊断比例减少,首次抑郁发作及双相躁狂的诊断比例增加;现在组使用第2代抗抑郁药、第2代抗精神病药及新型情感稳定剂的频率明显高于过去组,使用锂盐的频率明显降低;现在组抗抑郁药加情感稳定剂使用频率明显低于过去组,差异有统计学意义(P<0.05),而抗抑郁药加抗精神病药的使用比例明显高于过去组,差异有统计学意义(P<0.05),抗精神病药加情感稳定剂使用比例两组差异无统计学意义(P>0.05)。结论心境障碍的诊断分型越来越细,临床医生注重使用新型抗精神病药物增效治疗。Objective To understand the diagnosis types and prescription pattems chagnes of hospitalized patiems with meod disordevs in different times,and to provide a reference for clinical rational use of drugs.Methods The in Check-diagnosed with mood disorders Mental Health Center of Chongqing were divided into 2002 group（the last group）and 2007 group（now Group）,using CCMD-3 re-diagnosed,and two patients the diagnosis of subtypes of and drug use for statistical analysis and classification.Results Single-phase and recurrent manic depression diagnosis of the present group to reduce the proportion of first depressive episode and the diagnosis of bipolar manic increase in the proportion;now No.2 on behalf of the group＇s prescription anti-depressants,the first two-generation antipsychotics and new emotions.The frequency stabilizer significantly was higher than the last group,the frequency of prescription of lithium significantly reduced;the antidepressants plus mood stabilizers frequency of use pre...更多sent group was significantly lower than the last group（P〈0.05）,while the proportion of antidepressants plus antipsychotics was significantly higher than the latter（P〈0.05）,antipsychotics plus mood stabilizers using the ratio of two groups had no statistically significant difference（P〉 0.05）.Conclusion The diagnosis of mood disorder sub-type is getting smaller,clinicians focus on the use of new psychotropic substances,the treatment efficiency.

关 键 词：心境障碍 抗抑郁药 抗精神病药 情感稳定剂 

分 类 号：R749.4[医药卫生—神经病学与精神病学]