乳腺导管内癌前哨淋巴结活检术的临床意义  

Sentinel lymph node biopsy for patients with breast ductal carcinoma in situ

作　　者：孙晓[1] 王永胜[1] 周正波[1] 李永清[1] 刘雁冰[1] 陈鹏[1] 赵桐[1] 王蕾蕾[1] 李太玉[1] 

机构地区：[1]山东省肿瘤医院乳腺病中心,250117

出　　处：《中华内分泌外科杂志》2010年第1期28-31,共4页Chinese Journal of Endocrine Surgery

基　　金：中国抗癌协会乳腺癌专业委员会多中心协作项目（CBCSG-01）

摘　　要：目的探讨乳腺导管内癌（DCIS）行前哨淋巴结活检术（SLNB）的临床意义。方法凹顾性分析2002年1月至2007年6月行SLNB的86例乳腺DCIS及51例导管内癌微浸润（DCISM）临床资料，分析影响其前哨淋巴结（SLN）阳性率的因素。结果86例DCIS中，行保乳手术42例，乳房切除术44例，3例（3．5％）因SLN阳性改行腋清扫术，并均为唯一转移的腋淋巴结。51例DCISM中，行保乳手术13例，乳房切除术38例，4例（7．8％）SLN阳性，1例存在腋窝非前哨淋巴结转移。所有患者中位随访4年，均未见同侧腋窝复发及远处转移。结论DCISM应该常规行SLNB；行乳房切除手术的DCIS应同时行SLNB，行保乳手术者可不行SLNB。Objective To evaluate the roles of sentinel lymph node biopsy （SLNB） for patients with breast ductal carcinoma in situ （DCIS）. Methods A database containing 86 breast DCIS patients and 51 ductal carcinoma in situ with microinvasion （DCISM） patients who received SLNB from Jan. 2002 to Jun. 2007 was retrospectively analyzed. Results Of the 86 DCIS patients, 42 received breast conserving surgery and 44 received mastectomy. Three patients （3.5%） had sentinel lymph node （SLN） metastasis, and the SLN is the only lymph node with metastasis. Of 51 DCISM patients, 13 received breast conserving surgery and 38 received mastectomy. 4 patients （7.8%） had SLN metastasis and 1 had non sentinel lymph nodes metastasis. After a median follow-up of four years, none of the patients had ipsilateral axillary recurrence and further metastasis. Conclusions SLNB should be done in all DCISM patients and those DCIS patients who received masteetomy, and be avoided in those who received breast conserving surgery.

关 键 词：乳腺癌 导管内癌 微浸润 前哨淋巴结活检术 

分 类 号：R737.9[医药卫生—肿瘤]