急性脑梗死患者治疗前后血浆HCY、vWF和血清P-选择素水平检测的临床意义  

Clinical significance of detection of plasma HCY,vWF and serum P-selectin levels before and after treatment in patients with cerebral infarction

作　　者：徐丙超[1] 何明利[1] 徐英达[1] 赵绍林[1] 

机构地区：[1]徐州医学院附属连云港医院神经内科,江苏连云港222002

出　　处：《中国医药导报》2010年第6期33-34,共2页China Medical Herald

摘　　要：目的:探讨急性脑梗死患者治疗前后血浆HCY、vWF和血清P-选择素水平的变化及临床意义。方法:应用ELISA法对32例急性脑梗死患者进行血浆HCY、vWF和血清P-选择素水平检测,并与35例正常人进行比较。结果:患者组治疗前血浆HCY、vWF和血清P-选择素水平均显著高于正常人组(P<0.01),经溶栓等措施治疗1个月后与正常人比较,差异有统计学意义(P<0.05)。结论:检测急性脑梗死患者治疗前后血浆HCY、vWF和血清P-选择素水平的变化对了解病情及观察疗效均具有重要的临床价值。Objective：To explore the clinical significance of detection of plasma homocysteine （HCY）,von willebrand factor （vWF） and serum P-selectin levels before and after treatment in patients with cerebral infarction. Methods：Plasma HCY,vWF and serum P-selectin levels were determined by ELISA assay in 32 patients with cerebral infarction and 35 normal people. Results：Before treatment,the plasma HCY,vWF and serum P-selectin levels of patient group were signifi cantly higher than those of normal people group （P〈0.01）. One month after treatment,plasma HCY,vWF and serum P-selectin levels were also higher than those of normal people group （P〈0.05）. Conclusion：Detection of plasma HCY,vWF and serum P-selectin before and after treatment is important for understanding the pathogenetic condition and observing efficacy of patients with cerebral infarction.

关 键 词：脑梗死 HCY VWF P-选择素 

分 类 号：R743[医药卫生—神经病学与精神病学]