维生素C在肿瘤治疗中的作用研究进展  

Research Progress on Role of Vitamin C in Tumor Therapy

作　　者：荆晓娟[1] 杜冀晖[2] 贺克俭 

机构地区：[1]广东医学院附属深圳南山医院消化内科,广东深圳518052 [2]广东医学院附属深圳南山医院中心实验室,广东深圳518052 [3]深圳市西丽人民医院院长办公室,广东深圳518051

出　　处：《医学综述》2010年第4期554-557,共4页Medical Recapitulate

摘　　要：维生素C可以预防肿瘤,将其作为抗肿瘤药物运用于临床具有广阔的前景。维生素C抗肿瘤机制有:作为电子供体在细胞外液中产生过氧化氢杀伤肿瘤细胞;干扰肿瘤细胞周期,诱导肿瘤细胞凋亡等。但有研究报道维生素C可以对抗化疗药,将维生素C作为接受化疗的癌症患者的营养支持治疗有不利的影响。Vitamin C can prevent the process of tumorigeness,so it has an extensive prospect to act as an anticancer agent in clinical practice.The mechanisms of antagonizing cancer are as follows：kill cancer cells via generating hydrogen peroxide in extracellular fluid as the electron donor;interfere tumor cell cycle,induce tumor cell apoptosis and so on.But some studies have reported that vitamin C can counter chemotherapy,suggesting that vitamin C as nutritional support may have adverse consequences in patients who are receiving cancer chemotherapy.

关 键 词：维生素C 肿瘤 化疗药 

分 类 号：R730.53[医药卫生—肿瘤]