儿童使用APF凝胶和氟化泡沫氟的作用量及摄入量比较  

The Uptake and Exposure to Fluoride in Children: Comparison of APF gel and Foam

作　　者：胡德渝[1] 童冠雄[1] 李雪[1] 范旭[1] 魏建华[1] 张萍[2] 陈文英 

机构地区：[1]华西医科大学口腔医学院预防医学教研室,成都市610041 [2]卫生部口腔生物医学工程重点实验室,610041

出　　处：《口腔医学纵横》1998年第4期201-203,共3页Journal of Comprehensive Stomatology

摘　　要：目的检测中国儿童氟化泡沫使用量、滞留量并与含氟凝胶比较。方法研究对象为成都市、小学1年级学生（年龄6～7岁）105人，55人使用氟化泡沫、50人使用含氟凝胶。将含氟凝胶或泡沫放置在已称重的托盘后再称总重，按常规操作程序应用于实验对象。使用后收集唾液、托盘及盘中剩余药物。取出托盘2min及10min后，用事前称重塑料试管继续收集唾液2min。实验室检测采用盲法，使用氟离子电极检测样本氟浓度并计算回收的总氟量。结果6～7岁儿童平均使用0．52±0．10g的氟化泡沫和2．61±0．43g含氟凝胶。滞留的氟量氟化泡沫为1．76±0．72mg，含氟凝胶为6．75±4．56mg。氟化泡沫的用量为含氟凝胶重量的19．92％，吸收量为含氟凝胶的26．07％。结论　氟化泡沫有明显减少病人氟使用量的优点。:Objective To compare two topical APF products, a gel and foam, with respect to the amounts of productand fluoride applied salivary F concentrations. Methods The subjects included 105 children in Chengdu City. Fifty of thesubjects were treat for 4 min with the gel and the other 55 subjects with the foam. The salivary sample collect at the 2 and10 min after treat with fluoride products. Salivary F concentration after treatment with the gel or foam was analyzedusingthe ion-specific electrode and miniature calomel reference electrode. The chemical analyses were done in a 'blind' manner.Results The average amount of fluoride are 0. 52 ± 0. 10g for the foam and 2. 61 ± 0. 43g for the gel.The amounts of Fnot recovered from mouth were 1. 76 ± 0. 72 mg for the foam and 6. 75 ± 4. 56 mg for the gel. Conclusion Comparedwith the gel, only about one-fifth as much of the foam product is required for adequate coverage of the teeth, with significantly reduces F exposure and retention by the patient.

关 键 词：氟化泡沫 含氟凝胶 酸性磷酸氟 龋齿 预防 儿童 

分 类 号：R780.1[医药卫生—口腔医学] R788.101[医药卫生—临床医学]