经皮下植入式导管药盒系统肝动脉及门静脉同期化疗栓塞治疗肝细胞癌  

Combined hepatic arterial and portal venous chemoembolization in the treatment of primary hepatocellular carcinoma via port catheter system implanted subcutaneously on the same stage

作　　者：洪坚善[1] 莫钦国[1] 张传珉[1] 刘剑勇[1] 柳逸斌[1] 

机构地区：[1]广西医科大学附属肿瘤医院外科 [2]南宁市针灸医院外科

出　　处：《广西医学》1998年第6期1008-1010,共3页Guangxi Medical Journal

摘　　要：目的：评价经皮下植入式导管药盒系统（ＰＣＳ））行肝动脉及门静脉同期化疗栓塞治疗肝细胞癌的疗效。方法：对２５例开腹探查证实不能切除的中晚期肝细胞癌患者行肝动脉及门静脉双插管ＰＣＳ植入。术后经ＰＣＳ作肝动脉及门静脉同期化疗栓塞治疗。结果：（１）肿瘤缩小超过５０％者达６４％（１６／２５）。（２）ＡＦＰ降至正常者７３．３％（１４／１９）。（３）一年、二年生存率分别为９２％（２３／２５）、７２．２％（１３／１８）。（４）３例获Ⅱ期手术切除。结论：经植入式ＰＣＳ作同期肝动脉及门静脉化疗栓塞是治疗中晚期肝细胞癌一种行之有效的方法。Objective:To evaluate the therapeutic efficacy of combined hepatic arterial(HAE)and portal venous chemoembolization(PVE)in the treatment of primary hepatocellular carcinoma via port catheter system(PCS) Methods:The technique was used to treat advanced primary hepatocellular carcinoma in 25 cases of operative patients with unresectable tumor Catheters were introduced to hepatic artery and portal vein The ports were implanted subcutaneously in the right upper abdomen and conneted with the catheters HAE and PVE were done after implantion via PCS regularly Results:The diminution of tumor size(>50%)was found in 64% of patients(16/25) The survival rates were 92%(23/25) for 1 year and 72 2%(13/18)for 2 year Three patients gained chance of stage Ⅱ surgical resection after this therapy Conclusion:HAE combined with PVE via PCS on the same stage is safe and effective procedure for patients with advanced hepatocellular carcinoma Cure can be achieved only after stage Ⅱ resection

关 键 词：肝细胞癌 化疗栓塞 导管药盒系统 肝肿瘤 

分 类 号：R735.705[医药卫生—肿瘤]