实时超声造影在肝癌微创治疗术中的临床应用  

Value of real-time Sonovue-enhanced ultrasonography in assessing liver cancer treated with interventional therapy

作　　者：李敬东[1] 刘健[1] 赵学友[1] 袁顺娴[1] 张宁[1] 

机构地区：[1]川北医学院附属医院,四川南充637000

出　　处：《现代中西医结合杂志》2010年第9期1044-1045,1060,共3页Modern Journal of Integrated Traditional Chinese and Western Medicine

摘　　要：目的探讨超声造影技术在肝癌微创介入治疗前后的应用价值。方法41例肝脏恶性肿瘤患者接受了不同类型的微创介入治疗,于治疗前后采用超声造影技术对其中46个病灶进行造影增强超声检查。结果介入治疗前造影增强超声显示46个病灶表现为动脉早期抱球状、弥漫或轻度增强;治疗后病灶超声造影检查结果显示有18个病灶有残存活性、21个病灶完全灭活、7个病灶与治疗前无变化,与最终诊断比较,灵敏度为89%(25/28),特异度为100%(18/18),总符合率为93%(43/46),与数字剪影血管造影(DSA)检查结果比较无显著性差异(P>0.05),明显高于常规彩超结果(P<0.05)。结论实时超声造影可以提高肿瘤内血流信号检测,有助于确定介入治疗范围,是评价微创治疗疗效的有效方法。Objective It is to investigate the clinical value of contrast enhanced ultrasonography （CEUS） before and after interventional therapy of liver cancer. Methods 41 patients with liver neoplasms were accepted different type of interventional therapy. CEUS was performed before and after the interventional therapy procedure. Results 46 lesions were observed with CEUS before interventional therapy, which showed ball-carrying sign or diffuse enhancement. These lesions were observed with CEUS after interventional therapy, with partly enhancement in 18 lesions, no enhancement in 21 lesions and enhancement in 7 lesions. The sensitivity, specificity and diagnostic accuracy of CEUS for demonstrate intratumoral flow signals were 89% （25/28）, 100% （18/18）, 93% （43/46）, which were similar to the DSA （P 〉0.05） and were significantly superior to the routine color ultrasonography （ P〈 0.05）. Conclusion CEUS may provide more information on the feeding vessels of the tumor, which may be an effective method for assessing the treatment interventional therapy of liver cancer.

关 键 词：肝癌 超声造影 介入治疗 

分 类 号：R735.7[医药卫生—肿瘤]