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作 者:苏旭军[1] 张建中[1] 王裎鹏[1] 周婷婷[1]
出 处:《西部医学》2010年第3期502-503,共2页Medical Journal of West China
摘 要:目的观察不同剂量及分割方式下对骨转移癌疼痛的疗效。方法50例骨转移癌患者分为两组,常规分割组26例,40~50Gy/4~5周,5次/周,2Gy/次;大分割组24例,采用大分割快速照射,30Gy/2周,3次/周,5Gy/次。结果常规分割组CR53.8%,PR34.6%,MR3.8%,;大分割组CR54.1%,PR 33.3%,MR 4.1%。组间比较差异无统计学意义(P>0.05)。结论局部放射治疗是转移性骨肿瘤止痛有效方法,两种分割方式之间无明显差异。Objective To investigate the efficacy of relieve the pain of bone metastases with different fractionation schemes. Methods Fifty eases of bone metastasis were divided into two groups, the conventional radiotherapy and the big fraetionated radiotherapy. The conventional radiotherapy was performed in 26cases in the way of 40-50 Gy, 5 fractions/ week, 2 Gy/fraction, The big fractionated radiotherapy was performed in 24 cases in the way of 30Gy, 3fractions/week, 5Gy/fraction, and the two fraction schemes were practiced for the pain relief in the patients. Result The CR of group 1 was 53, 8 %, PR 34, 6 % MR 3.8 %. The CR of group 2 was 54.1% in the big fractionated group, PR rate was 33.3 %, MR rate was 4.1%. There was no significant difference between the different fractionation schemes for pain relief(P〉 0. 05). Conclusion Radiotherapy is an effective pain relief measurement and the efficacy is not different between the two different fractionation schemes.
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