宫颈环形电切除术治疗宫颈上皮内瘤变155例临床分析  

Loop Electrosurgical Excision Procedure in the Treatment of Cervical Intraepithelial Neoplasia——155 Cases Analysis

作　　者：何素芬 金绍辉 唐良萏[2] 

机构地区：[1]重庆市西郊医院,重庆400051 [2]重庆医科大学附属第一医院,重庆400016

出　　处：《实用妇产科杂志》2010年第2期115-117,共3页Journal of Practical Obstetrics and Gynecology

摘　　要：目的:探讨宫颈环形电切除术(LEEP)治疗宫颈上皮内瘤变(CIN)的临床价值。方法:对经阴道镜下宫颈活检诊断为CIN的155例患者采用LEEP宫颈锥切,观察手术时间、出血量,比较术前宫颈活检与术后病理检查结果,随访疗效和宫颈塑形情况。结果:LEEP治疗CIN平均时间6.8分钟,出血量9.6ml,阴道镜下宫颈活检的CINⅠ、CINⅡ、CINⅢ与LEEP术后标本的病理诊断CINⅠ、CINⅡ、CINⅢ呈正相关,相关系数rs=0.785(P<0.01),治愈率为98.7%(149/151),151例中宫颈塑形满意134例(88.7%)。结论:LEEP是诊断和治疗CIN安全有效的方法。Objective：To study the effectiveness of Loop electrosurgical excision procedure （LEEP）in the diagnosis and management of cervical intraepithelial neoplasia（CIN）. Methods ：155 patients with CIN were diagnosed by cervical biopsy under colposcopy. All cases were treated with LEEP and the operative time, bleeding volume ,cervical biopsy results before and after LEEP were evaluated,and the effects and cervical regeneration were followed up. Results： The mean operative time of LEEP was 6.8 minutes. The mean bleeding volume was 9.6ml. Pathological diagnosis of CINⅠ CINⅡ CINⅢ after LEEP were positively correlated to directed biopsy by colposcopy. The correlation coefficient was 0. 785 （ P 〈 0.01 ）. The cure rate of LEEP was 98.6%. Among the 151 cases, 134 （ 88.7% ） were satisfactory cervical regeneration. Conclusions：LEEP is one of the effective and safe methods for the diagnosis and treatment of CIN.

关 键 词：宫颈上皮内瘤变 宫颈环形电切除术 宫颈塑形 

分 类 号：R737.33[医药卫生—肿瘤]