110例肿瘤患者治疗前后体液及分泌物的细菌学检查及药敏试验分析  

BACTERIOLOGICAL DETECTION AND SENSITIVITY TESTS OF SECRETATION OF 110 PATIENTS WITH CANCERSBEFORE AND AFTER TREATMENT

作　　者：湛学军[1] 邹飞[2] 周炳能[2] 

机构地区：[1]江西省医学科学研究所 [2]江西省肿瘤医院

出　　处：《九江医学》1998年第3期155-157,共3页Jiujiang Medical Journal

摘　　要：目的：了解肿瘤患者经各种治疗后病原菌感染状况及对抗生素的敏感性。方法：对１１０例肿瘤患者治疗前、后的体液、分泌物标本进行细菌学分析；对治疗后所分离的部分菌株进行药敏感试验。结果：治疗前分离出革兰阳性菌３５株，阳性率为３０４３％；革兰阴性菌４１株，阳性率为３５１５％；类酵母菌１２株，阳性率为１０４３％。治疗后分离出革兰阳性菌３６株，阳性率为３１３０％；革兰阴性菌６５株，阳性率为５６５２％；类酵母菌３２株，阳性率为２７８３％。与治疗前相比，革兰阴性菌、类酵母菌感染明显上升（Ｐ＜００１），且革兰阴性菌中以大肠埃希氏菌和铜绿假单胞菌占优势。结论：肿瘤患者经各种治疗后，条件致病菌和类酵母菌的感染率正逐渐升高。OBJECTIVE:To study vulnerability to pathogens and sensitivity to antibiotics of the patients with cancers after treatments.METHOD:We analyzed and compared 110 patients with cancer before and after treatment in bacteriology.Isolated bacteria strains were conducted antibiotics sensitivity test.RESULTS:Before treatment,we isolated G + bacteria 35 strains,G - bacteria 41,yeast-like bacteria 12.Their positive rate is 30 43%,35 15%,10 43% respectively.After treatment,we isolated G + bacteria 36 strains,G - bacteria 65,yeast-like bacteria 32,and positive rate is 31 30%,56 52%,27 83% respectively.Compared with former,infection rate of G - and yeast-like bacteria significantly increased ( P <0 01) and most of G + bacteria are Clinic E.coli strains and pseudomona aeruginosa PA. CONCLUTION:Infection rate by conditional pathogens and yeast-type bacteria increases in patients with cancers after treatment.

关 键 词：细菌学分析 肿瘤 体液 分泌物 药敏试验 

分 类 号：R730.53[医药卫生—肿瘤] R969.4[医药卫生—临床医学]