肝脏血流灌注指数在大肠癌肝转移中的临床意义  

The clinical significance of the DPI in the patients with hepatic metastases of colorectal carcinoma

作　　者：郭昊[1] 章志翔[1] 朱理玮[1] 

机构地区：[1]天津医科大学总医院普通外科,天津300052

出　　处：《天津医科大学学报》2010年第1期75-77,80,共4页Journal of Tianjin Medical University

摘　　要：目的:检测大肠癌患者的肝脏血流灌注指数(DPI),探索大肠癌肝转移患者DPI变化的规律。方法:(1)选取术前大肠癌患者37例(分为肝转移组10例与无肝转移组27例)和同期选取30例健康人群作为对照组。(2)对全体受试对象进行彩色多普勒超声检测肝脏血流状况,并由计算机计算出DPI(肝动脉血流量/全肝血流量)。结果:根据病理结果及影像学资料对大肠癌病例进行分组比较证明大肠癌肝转移组患者的DPI值明显高于无肝转移组和健康对照组(P<0.05),准确率达100%;无肝转移组与对照组之间的差异无统计学意义(P>0.05)。结论:DPI可作为检测大肠癌肝转移的指标,并为大肠癌患者提供了一种简便、有效的术后随访手段。Objective： To investigate the variation of Doppler Perfusion Index （DPI） in patients with liver metastases of colorectal carcinoma by color doppler sonography. Methods： （1） 67 objects were involved, including 37 colorectal carcinoma patients （liver metastases group 10 cases and without liver metastases group 27 cases）and 30 healthy cases as control group. （2） In tested objects, hepatic Perfusion by colour Doppler flow imaging was detected and the DPI （hepatic arterial/total liver blood supply） was computed. Results： According to pathology and imaging results, the DPI of patients with colorectal liver metastases was significantly higher than that in healthy control group and without liver metastases group （P〈0.05）with appearing the index accuracy of 100%; the difference between without liver metastases group and the control group was not significant （P〉0.05）. Conclusion： DPI may be a monitoring factor to screen hepatic metastases in patients with colorectal cancer and serve as a practical measurement in postoperative following-up.

关 键 词：大肠癌 肝脏转移:肝脏血流灌注指数 

分 类 号：R735.34[医药卫生—肿瘤]