物体记忆测验的北京老年常模及其在轻度认知损害流行病学筛查中的应用  

Beijing norms of Fuld object memory evaluation and its application in mild cognitive impairment screening

作　　者：郭敏[1] 周卫东[2] 汤哲[3] 

机构地区：[1]航天中心医院神经内科,100049 [2]北京三博脑科医院神经内科,100093 [3]首都医科大学宣武医院社会医学部,100053

出　　处：《中国神经免疫学和神经病学杂志》2010年第2期120-122,142,共4页Chinese Journal of Neuroimmunology and Neurology

摘　　要：目的建立Fuld物体记忆测验(Fuld object memory evaluation,FOM)量表的北京城乡老年人常模,并分析其在筛查轻度认知损害(mild cognmve impairment,MCI)中的作用。方法采用随机分层抽样方法选取北京城乡60岁及以上居民715名,其中健康人504名(男230名,女274名)及MCI患者211例(男94例,女117例),对其进行FOM测验和其他多种神经心理量表检查。神经内科医师结合临床和纵向资料根据相应诊断标准明确诊断,然后对数据进行统计学分析。结果老年人常模各年龄段界限值:60～70岁<15分,70岁以上组<14分;首次回忆得分筛查MCI的界限值为6分。结论 FOM能检出患者以记忆为主的认知功能障碍,操作简便,敏感度适中,可作为临床和流行病学筛查MCI的有效工具。Objective A Chinese version of Fuld object memory evaluation （FOM） was studied to set a norm in urban and rural areas in Beijing Chinese population. The screening validation of FOM in mild cognitive impairment was investigated as well in this study. Methods 715 subjects （age range 60-96 years old） were selected by a stratified random sampling procedure from Beijing urban and rural. 504 cases were norm （230 males, 274 females）, and 211 （ 94 males, 117 females） were suffered from mild cognitive impairment. The investigation was conducted by well-trained interviewer. The FOM was administered to all participants. Sensitivity and specificity of FOM were assessed for detection of mild cognitive impairment （MCI）. Results The cut-off scores for screening MCI from the community is 15 for those of 60-70 years old, 14 for those older than 70 years. Conclusions The Chinese version of FOM is convenient to administrate and has moderate sensitivity to screen MCI. The norms of FOM in Beijing community are useful in MCI screening in clinical and epidemiology settings.

关 键 词：轻度认知损害 Fuld物体记忆测验 

分 类 号：R749.15[医药卫生—神经病学与精神病学]