乳腺癌术后放疗致放射性肺炎的临床分析  

Clinical Analysis of Postoperative Radiation Pneumonitis of Patients with Breast Cancer

作　　者：麦茂[1] 张惠敏[2] 梁文勇[1] 方伟达[1] 

机构地区：[1]开平市中心医院肿瘤科,广东开平529300 [2]开平市中心医院内科,广东开平529300

出　　处：《肿瘤基础与临床》2010年第1期44-46,共3页journal of basic and clinical oncology

摘　　要：目的探讨乳腺癌术后放疗引起放射性肺炎的相关临床因素。方法回顾性分析226例术后放疗的乳腺癌,观察放疗的照射野、照射剂量,使用化疗药物的时间、种类,内分泌治疗,患者的年龄和肺部基础病变与放射性肺炎发生率的关系。结果发生放射性肺炎29例,放射性肺炎的发生率与照射野、照射剂量和使用化疗药物的时间有关(P<0.05),与化疗药物种类和肺部基础病变也有一定关系。结论照射野和剂量的增加、放疗前化疗及肺部基础病变均会增加放射性肺炎的发生率。Objective To identify the clinical relative factors of radiation pneumonitis of patients with breast cancer.Methods 226 patients with breast cancer who had received postoperative radiotherapy were analysed,the relationship between the incidence of radiation pneumonitis and radiation field,radiation dose,chemotherapy schedule,chemotherapy drugs,endocrine therapy,age,underlying disease of the lung were observed.Results 29 patients developed radiation pneumonitis.The incidence of radiation pneumonitis were related with radiation field,radiation dose and timing of chemotherapy（P〈0.05）;and there are certain relationships with drugs of chemotherapy,underlying disease of the lung too.Conclusion Increasing in radiation field and dose,chemotherapy before radiotherapy and underlying disease of the lung can increase the incidence of radiation pneumonitis of patients with breast cancer.

关 键 词：乳腺癌 放射治疗 放射性肺炎 

分 类 号：R737.9[医药卫生—肿瘤] R730.58[医药卫生—临床医学]