小剂量尿激酶治疗频发短暂性脑缺血发作的临床研究  

Low-dose urokinase in the treatment of frequent transient ischemic attack

作　　者：袁亮方[1] 姜国晶[1] 张红[1] 扬文丽[1] 

机构地区：[1]天津市第三医院神经内科,天津300250

出　　处：《吉林医学》2010年第7期891-892,共2页Jilin Medical Journal

摘　　要：目的:研究小剂量尿激酶对频发TIA干预治疗的疗效。方法:67例TIA住院患者随机分为两组,治疗组(小剂量尿激酶组)36例和对照组31例(常规治疗组),治疗组在常规治疗组的基础上加用小剂量的尿激酶治疗,两组的疗效进行比较。结果:两组疗效比较差异有统计学意义(P<0.01),治疗组的疗效明显优于对照组;并且在部分形成脑梗死的患者其残疾程度治疗组明显优于对照组。结论:在常规治疗的基础上,加用小剂量的尿激酶对频发的TIA患者进行干预治疗,可以有效的治疗TIA;并减少其形成脑梗死的残疾程度。Objective To explore the efficacy of low-dose urokinase in the treatment of frequent transient ischemic attack（TIA） patients.Method Total 67 cases of TIA were randomly divided into two groups,36 cases in the treatment group（low-dose urokinase group） and 31 cases in the control group（conventional treatment group）.Low-dose urokinase was used in the treatment group compared with the conventional treatment group.Results Difference in efficacy between the two groups was significant（P0.01）,the efficacy of the treatment group was superior to the control group;and the extent of disability formation of cerebral infarction patients in the treatment group was significantly lower than the control group.Conclusion At the basis of conventional therapy,adding a small dose of urokinase for patients with TIA could be effective and reduce the formation of cerebral disability.

关 键 词：TIA 小剂量 尿激酶 

分 类 号：R743.3[医药卫生—神经病学与精神病学]