弱视儿童治疗前后PR-VEP P_(100)波变化探讨  

Study on change of PR-VEP P 100 wave before and after treatment in amblyopia children .

作　　者：徐国兴[1,2,3] 洪金针[1,2,3] 林玲[1,2,3] 林发森 何青[1,2,3] 侯丽枫 刘宝英[1,2,3] 

机构地区：[1]福建医科大学附属第一医院眼科 [2]福建省眼科研究所 [3]福建医科大学预防医学系

出　　处：《中国斜视与小儿眼科杂志》1998年第4期154-156,共3页Chinese Journal of Strabismus & Pediatric Ophthalmology

摘　　要：目的为了进一步评价弱视治疗前后全视野图形反转视诱发电位Ｐ１００波变化。方法随机选择２９例（５８眼）弱视儿童及３０例正常儿童，两组年龄均４～１２岁，采用Ｎｏｍａｄｌｅ电生理仪进行电生理检查。结果发现弱视组ＰＲ－ＶＥＰＰ１００振幅明显低于正常对照组；潜伏期则比正常对照组明显延长。弱视经治疗后，其视力达０９～１０时，ＰＲ－ＶＥＰＰ１００潜伏期与治疗前的Ｐ１００潜伏期比较明显缩短。结论弱视儿童的ＰＲ－ＶＥＰＰ１００振幅降低，Ｐ１００潜伏期延长。弱视经治疗，视力达基本正常时Ｐ１００潜伏期可以逆转；Abstract Objective Electrophyology has been extensively applied in amblyopia studies. We also evaluated visual evoked potential (VEP) in amblyopia and normal children with full field pattern reversal stimulation. Methods 29 children (58 eyes) with amblyopia randombly selected from our clinic and 30 normal Children both aged 4～12 were electrophyologically examined by using Nomadle model. Results In the amblyopia group before treatment, the PR-VEP P 100 amplitude was significantly lower than that in control group (11 16±6 74μV,n=56, vs 16 78±5 55μV, n=60). The latency was signifcantly (P<0 01) prolonged in amblyopia eyes compared with control eyes (110 39±10 01ms, n=56 vs 101 81±4 38ms, n=60). Conclusion Our results indicate that the decrease of VEP amplitude and prolonged latency are well consistent with other reports and reduced visual acuity in children with amblyopia tends to aggravate VEP parameter. The latency of PR-VEP P 100 in amblyopia children can be recovered after visual acuity return to normal level by treatment, but the amplitude can not be clearly.

关 键 词：图形反转 视诱发电位 弱视 儿童 综合疗法 

分 类 号：R777.440.5[医药卫生—眼科]