原发性脑脊膜黑色素瘤  

Primary leptomeningeal melanoma

作　　者：彭斌[1] 黎辉[2] 彭善友[2] 

机构地区：[1]湖北医科大学附一医院眼科,430060 [2]湖北医科大学附一医院病理科,430060

出　　处：《卒中与神经疾病》1998年第4期214-216,共3页Stroke and Nervous Diseases

摘　　要：原发性脑脊膜黑色素瘤较罕见。本文报告4例,其特点系脑膜或脊膜有黑色素瘤而皮肤、眼球和内脏没有黑色素瘤。该病来源于软脑膜或软脊膜的黑色素细胞。临床症状和体征呈多样性和非特异性,故诊断困难,主要依靠病理检查,手术切除仍是目前主要治疗方法。4例中随访3例,术后生存4个月1例,生存5、6年各1例。Four patients with primary leptomeningeal melanoma(PLM).diagnosed by pathological examination,were reported.Three of them were followed-up,in which 2 cases survived for 5 and 6 years respectively and I case survived for 4 months post-operatively.The PLM,which is extremely rare,originates from the melanophore of pia mater and does not develops in skin,eyes and viscera,and is difficult to diagnose due to its multiplicity and non-particularity of the clinical symptoms and signs.

关 键 词：黑色素瘤 病理学 脑脊膜肿瘤 

分 类 号：R739.450.2[医药卫生—肿瘤] R739.502[医药卫生—临床医学]