免煎方剂中药对草酸钙结晶生长影响的研究  

The Study of the Effect of Non-decoctting Chinese Traditional Medicine on the Growth of Calcium Oxalate Crystal

作　　者：黄小平 陈协辉 陈丽萍 苏娜 潘达亮 黄进明 陈日来 

机构地区：[1]广东省深圳市福田区第二人民医院,518049

出　　处：《医学研究杂志》2010年第3期73-76,共4页Journal of Medical Research

基　　金：广东省中医药管理局科研课题(2007251)

摘　　要：目的探讨三金三子汤免煎方剂中药对草酸钙结晶生长的影响。方法采用45Ca—CaCl2掺入的结晶生长动力学模型，研究不同作用时间免煎方剂中药对草酸钙结晶生长的影响。结果从免煎方剂中药组5min滤液内cpm％明显减少，与对照组同时间点的水平相当，20～120min诸时间点的cpm％与对照组比较，cpm％减少幅度甚小，甚至接近回复总放管水平。结论免煎方剂中药对草酸钙结晶生长有明显的抑制作用，抑制作用与用药时间呈依赖关系。为临床应用此免煎方剂中药临床治疗球路结石患者提供一定的试验依据。Objective To explore the effect of san jin san zi soup non - decoctting Chinese traditional medicine on the growth of cal- cium oxalate crystal. Methods We applied the 45 Ca - CaC12 incorporated crystal growth kinetic model and investigated the effect of non - decoctting Chinese traditional medicine on the growth of calcium oxalate crystal on different action time. Results The filtrate＇s cpm percentage（ % ） obviously decreased after the non - decoetting Chinese traditional medicine actted 5 minutes, which was as much as that of the control group concurrent testing. The filtrate＇s epm% decreased less significantly than that of the control group after the non - decoctting Chinese traditional medicine actted from 20 minutes to 120 minutes, and even it was approximately near to the initial level. Conclusion The non - deeoctting Chinese traditional medicine has the inhibitory action on the the growth of calcium oxalate crystal, and the inhibitory action depends on the medicating time, which providing some evidence for the doctors to treat the lithangiuria patients by use of the nondeeoetting Chinese traditional medicine.

关 键 词：中药 草酸钙结晶 

分 类 号：R364.25[医药卫生—病理学]