弹性颅内动脉瘤的数值模拟分析  

Numerical simulation in analysis of hemodynamic changes in intracranial aneurysm with elastic wall

作　　者：卢海涛[1] 黄清海[1] 刘建民[1] 陈家亮[2] 王盛章[2] 

机构地区：[1]第二军医大学长海医院神经外科,上海200433 [2]复旦大学力学与工程科学系,上海200433

出　　处：《第二军医大学学报》2010年第3期233-237,共5页Academic Journal of Second Military Medical University

基　　金：上海市自然科学基金(08ZR1404200);上海市优秀学科带头人计划(07XD14026)~~

摘　　要：目的探讨弹性颅内动脉瘤血流动力学变化,分析动脉瘤壁的力学特点对其的影响。方法结合数字减影血管造影(DSA)影像,借助计算流体力学(CFD)有限元方法的软件,采用计算流体-固体耦合分析,研究颅内动脉瘤弹性壁模型中的血液流动和管壁运动的相互耦合过程,及其对血流动力学数值模拟结果的影响。结果弹性壁时动脉瘤形态发生改变,动脉瘤和载瘤动脉的夹角也发生改变,使射入流在动脉瘤内的流场分布和壁面剪应力在动脉瘤壁表面分布受到影响。结论CFD数值模拟能直观反映动脉瘤的血流动力学特点;为了更好地进行颅内动脉瘤血流动力学参数的定量分析,应该采用更为准确的弹性壁模型。Objective To use numerical simulation for analying hemodynamic changes in intracranial aneurysm with elastic wall,and to analyze the effect of mechanical properties of the aneurysm wall on the hemodynamic changes.Methods Based on the DSA images of a patient with multi-intracranial aneurysm,the numerical simulation of the hemodynamics of the elastic intracinal aneurysm was processed using a software of finite element method of computational fluid dynamics（CFD） and the computational fluid-structure interaction analyses.We also investigated the effect of the coupling of hemodynamics and aneurysm wall movement.Results The morphology of the elastic aneurysm underwent deformation,and the angle between aneurysm and parent artery also changed,affecting the inflow jet dispersed into the flow field of aneurysm and the distribution of wall shear stress on the surface of aneurysm.Conclusion The numerical simulation of CFD can directly reflect the hemodynamic characteristics of aneurysms.More accurate elastic wall aneurysm model is needed to improve the quantitative analysis of the hemodynamics of intracranial aneurysms.

关 键 词：颅内动脉瘤 血流动力学变化 计算流体力学 流体-固体耦合 弹性壁 载瘤动脉 数值模拟分析 后交通动脉瘤 壁面剪应力 血流动力学参数 

分 类 号：R743[医药卫生—神经病学与精神病学]