3种肠内营养方案治疗急性脑梗死患者疗效及药物经济学比较  

Enteral Nutritional Schemes for Patients with Acute Cerebral Infarction:A Pharmacoeconomic Analyses

作　　者：朱蓓蕾[1] 王贞[1] 殷为勇[1] 张征[1] 叶强[1] 冯靓[1] 

机构地区：[1]温州医学院附属第一医院脑血管科,浙江温州市325000

出　　处：《中国康复理论与实践》2010年第3期258-259,共2页Chinese Journal of Rehabilitation Theory and Practice

基　　金：温州市科学技术局科技计划项目(Y20090421)

摘　　要：目的评价不同肠内营养方案治疗急性脑梗死患者的临床疗效及经济效果。方法急性脑梗死伴吞咽障碍患者117例,随机分为3组:分别给予鼻饲匀浆膳食、序贯肠内营养制剂、整蛋白肠内营养制剂治疗。14d后观察各组临床疗效并应用药物经济学方法进行成本-效果分析。结果各组临床有效率分别为42.5%、75%、49%,成本-效果比分别为9.48、29.37、42.16。结论对于急性脑梗死伴吞咽障碍患者,序贯肠内营养制剂效果最佳,鼻饲匀浆膳食最经济。Objective To evaluate the enteral nutritional schemes for patients with acute cerebral infarction in effectiveness and economy. Methods 117 acute cerebral infarction patients with dysphagia were divided into 3 groups. Homogenized diet, sequential intestinal nutrition and intestinal integral protein were provided respectively for these groups by nasogastric tube feeding. The clinical effectiveness was evaluated and the cost effectiveness analysis was done pharmacoeconomically 14 d later. Results The effective rates of these schemes were 42.5%, 75% and 49%, while the cost-effectiveness ratios were 9.84, 29.37, 42.16 respectively. Conclusion For the acute cerebral infarction patients with dysphagia, the scheme of sequential intestinal nutrition is most effective, and the homogenize diet is most economical.

关 键 词：脑梗死 吞咽障碍 肠内营养 药物经济学 成本-效果分析 

分 类 号：R743.2[医药卫生—神经病学与精神病学]