肛管直肠恶性黑色素瘤11例临床分析  

Clinical analysis of 11 cases with anorectal malignant melanoma

作　　者：帕尔哈提.沙依木 艾克热木.玉苏甫[1] 王海江[1] 艾孜买提.热合木吐拉[1] 

机构地区：[1]新疆医科大学附属肿瘤医院胃肠外科,新疆乌鲁木齐830011

出　　处：《新疆医科大学学报》2010年第1期73-74,共2页Journal of Xinjiang Medical University

摘　　要：目的探讨肛管直肠恶性黑色素瘤的临床特点及预后。方法对2002年7月～2008年5月在新疆医科大学附属肿瘤医院胃肠外科诊疗的11例肛管直肠恶性黑色素瘤患者的临床病理特点、治疗方法及预后进行回顾性分析。按治疗方式将患者分为2组:手术组(手术+辅助治疗)和非手术组(单纯辅助治疗)。结果手术组7例病人均行腹会阴联合切除术,术后平均生存22个月,最长存活60个月;非手术组4例采用免疫加中药等治疗,平均存活7个月。11例均获得随访,无失访者,随访时间4～60个月。结论肛管直肠恶性黑色素瘤预后差,治疗以手术根治及腹股沟淋巴结清扫为主,非手术治疗生存周期短,预后差,早期诊断和治疗是提高生存率的关键。Objective To investigate the clinical features and prognosis of anorectal malignant melanoma. Methods From July 2002 to May 2008, 11 cases of anorectal malignant melanoma of the clinical and path ological characteristics, treatment and prognosis were retrospectively analyzed. The patients were divided into two groups according to treatment： surgery＋adjuvant therapy and adjuvant therapy alone groups. Results Seven cases of abdominal perineal resection, mean survival after 22 months, the longest survival of 60 months; immune increase the use of four cases of non-surgicaltreatment of Chinese medicine, with an average survival of 7 months. 11 cases were followed up, no case was lost, the follow-up period was 4 months to 60 months. Conclusion The anorectal malignant melanoma and poor prognosis, treatment with radical surgery and inguinal lymph node dissection-based, non surgical treatment of short life cycle and poor prognosis, early diagnosis and treatment is the key to improve the survival rate.

关 键 词：直肠 黑色素瘤 临床分析 

分 类 号：R735[医药卫生—肿瘤]