麦默通微创活检系统对乳腺肿块诊断的应用价值  

Mammotome vacuum-assisted breast biopsy:Its application value in the diagnosis of breast diseases

作　　者：顾军[1] 于泽平[1] 王少华[1] 张晓薇[1] 赵善鹏[1] 季洪爱[2] 

机构地区：[1]南京军区南京总医院普通外科,南京医学博士210002 [2]南京军区南京总医院病理科,南京210002

出　　处：《医学研究生学报》2010年第3期279-281,共3页Journal of Medical Postgraduates

基　　金：南京军区南京总医院科研基金(2005045)

摘　　要：目的麦默通微创活检系统(mammotone biopsy system,MBS)为一种真空辅助粗针活检系统,比细针穿刺取材所获样本量更大。在乳腺疾病的诊断中应用日益广泛。文中评估MBS微创活检在乳腺肿块诊断中的应用价值。方法67例乳腺肿块患者(62例乳腺癌、5例乳腺炎症疾病)术前行超声引导下MBS穿刺。1 207例乳腺癌患者术前行细针穿刺检查,对两种方法的诊断价值进行评价。结果67例患者MBS穿刺成功率为100%。乳腺癌患者MBS穿刺的阳性率为98.4%,细针穿刺的阳性率为88.4%(P<0.05),两种方法的假阳性率均为0。MBS穿刺皮下血肿的发生率为7.4%(5/67),皮下瘀斑发生率为25.4%(17/67)。细针穿刺的患者无发生皮下血肿和皮下瘀斑者。结论细针穿刺法简便、安全、创伤小,缺点为阳性率较低、漏诊率较高。麦默通穿刺法具有高敏感、高特异性、微创的优点,可作为乳腺肿块定性的首选方法。Objective Mammotome is a vacuum-assisted core needle biopsy system,which can get larger volume of tissue than fine needle biopsy,and is obtaining a wider application in the diagnosis and treatment of breast diseases.This study aimed to explore the clinical value of mammotome vacuum-assisted breast biopsy in the diagnosis of breast diseases.Methods Sixty-seven patients with breast diseases,including 62 cases of breast cancer and 5 cases of inflammatory breast disease,underwent ultrasound guided mammotome vacuum-assisted breast biopsy,and 1 207 breast cancer patients received fine needle aspiration cytology（FNAC）,all before the operation.The two diagnostic methods were evaluated.Results The positive rate of mammotome biopsy was 98.4%,and that of FNAC was 88.4% in the detection of breast cancer（P 0.05）.The false-positive rate of both the methods was zero.The rate of subcutaneous hematoma in mammotome biopsy was 7.4%（5/67） and that of ecchymoma was 25.4%（17/67）.No subcutaneous hematoma and ecchymoma occurred in the FNAC group.Conclusion FNAC is convenient and safe,but has a lower positive rate than mammotome biopsy.While mammotome biopsy,characterized by minimal invasiveness,high accuracy and high specificity is recommended as the first choice for the definitive diagnosis of breast diseases.

关 键 词：麦默通 活检 乳腺癌 细针穿刺 超声引导 

分 类 号：R730.4[医药卫生—肿瘤]