广泛性焦虑症心理与药物治疗效果研究  

Effect on Psychotherapy and Drug Treatment for Generalized Anxiety Disorder

作　　者：孙正海[1] 李荐中[1] 王文林[1] 闫凤武[1] 

机构地区：[1]中国.齐齐哈尔医学院精神卫生学院精神医学教研室,161006

出　　处：《中国健康心理学杂志》2010年第3期272-274,共3页China Journal of Health Psychology

摘　　要：目的探讨广泛性焦虑症心理与药物治疗效果。方法将72例广泛性焦虑症患者随机分为研究组和对照组各36例。研究组使用心理治疗联合抗焦虑药物治疗,对照组单纯使用抗焦虑药物治疗。分别于治疗前和治疗第2、4、8周末采用汉密尔顿焦虑量表(HAMA)和焦虑自评量表(SAS)进行疗效评定,用副反应量表(TESS)评定不良反应。结果治疗8周后研究组有效率为94.4%,对照组有效率为72.2%,两组有效率比较有明显差异(P<0.05)。治疗后两组汉密尔顿焦虑量表总分和焦虑自评量表评分较治疗前都有所降低,研究组在治疗第4、8周末HAMA、SAS评分下降更明显,与对照组比较差异显著(P<0.01)。且研究组使用药物剂量明显低于对照组(P<0.05),不良反应较少。结论与单纯药物治疗相比,心理联合抗焦虑药物治疗广泛性焦虑,有效率增加,能够减少服药剂量和药物副反应,是治疗广泛性焦虑的有效方法,对缩短病程、预防复发有积极意义。Objective To investigate the effect of psychotherapy and drug treatment for Generalized Anxiety Disorder（GAD）.Methods A total of 72 patients with generalized anxiety disorder were randomly divided into study group（36 cases treated with psychotherapy combination drug treatment） and control group（36 cases only given anti-anxiety drugs）.The evaluation of curative effect was carried out before and at the ends of the 2th,the 4th,and the 8th weeks after treatment respectively by means of Hamilton Rating Scale for Anxiety（HAMA） and Self-Rating Anxiety Scale（SAS）.And the adverse effects was evaluated by means of Treatment Emergent Symptoms Scales（TESS）.Results After 8 weeks,94.4% of the study group and 72.2% of the control group were effective.The difference between the two groups was significant（P〈0.05）.The scores of HAMA and SAS decreased in post-treatment in both two groups.The scores of HAMA and SAS of study group decreased obviously at the end of the 4th and the 8th weeks,and there was different significantly from the control group（P〈0.01）.The total dose was lower than that of the control group significant（P〈0.05）,and the adverse effects were less in study group than in control group. Conclusion Compared with only medication for the GAD,the psychotherapy combination drug treatment can reduce the dosage and adverse effects,and increase the effective rate,the psychotherapy combination drug treatment is an effective method for the treatment of GAD,and it has active effect for shorting course of diseases and preventing recurrence.

关 键 词：广泛性焦虑症 心理联合药物治疗 药物治疗 疗效 

分 类 号：R749.99[医药卫生—神经病学与精神病学]