清热利胆合剂与熊去氧胆酸片治疗慢性胆囊炎疗效比较  

The Healing Efficacy Comparison of Treatment Chronic Cholecystitis with Qingrelidan Heji and Ursodeoxycholic Acid Tablets

作　　者：郭铁砚 刘静 王文星 

机构地区：[1]河北省迁安市中医院急诊科,迁安064400

出　　处：《中国医药导刊》2010年第3期425-426,共2页Chinese Journal of Medicinal Guide

基　　金：河北省中医药管理局2008年科研立项课题(2008148)

摘　　要：目的:探讨清热利胆合剂与熊去氧胆酸片治疗慢性胆囊炎的临床比较。方法:选取肝胆湿热型慢性胆囊炎150例,随机分为两组。清热利胆合剂治疗组70例,熊去氧胆酸片对照组80例,探讨两组疗效比较及对血浆肿瘤坏死因子(TNF-α)、β-内啡肽(β-EP)、血清超氧化物歧化酶(SOD)的影响。结果:两组总有效率比较差异无统计学意义,P>0.05,治疗前后两组TNF-α,β-EP值均减小,且P<0.05;对照组SOD较治疗前上升,且P>0.05;治疗组SOD较治疗前上升,且P<0.05。结论:两组均能改善TNF-α,β-EP指标,并且清热利胆合剂在改善SOD方面明显优于熊去氧胆酸片。Objective：To explore the healing efficacy comparison of trcatment chronic cholecystitis with Qingrelidan Heji and Ursodeoxycholic Acid Tablets.Methods：Select 150 eases of chronic cholecystitis with dampness and heat in liver and gallbladder,divided into two groups randomly.70 cases in the Treatment group used Qingrelidan Heji.80 cases in the contrast group used Ursodeoxycholic Acid Tablets,to explore the healing efficacy comparison and observe the influence of TNF-α, β-EP and SOD.Results：The total effective rate of the two groups has no statistically significant differences（P〉0.051.the TNF-α and β-EP reduce of the 2 groups before and after treatment（P〈0.05）,the SOD rising and the Treatment group rising distinctly （P〈0.05,P〈0.05 ） before and after treatment.Conclusion：The two groups all can improve TNF-α and β-EP, but Qingrelidan Heji better than Ursodeoxycholic Acid Tablets in improve SOD.

关 键 词：清热利胆合剂 熊去氧胆酸片 慢性胆囊炎 

分 类 号：R575.6[医药卫生—消化系统]