清胰汤保留灌肠对重症急性胰腺炎患者血清C反应蛋白水平的影响  

Effects of Qingyi Decoction Retention Enema on the Levels of C-reactive Protein in Severe Acute Pancreatitis

作　　者：钟玲红[1] 金育德[1] 

机构地区：[1]浙江省湖州市第一人民医院,湖州313000

出　　处：《中国中医急症》2010年第3期382-384,共3页Journal of Emergency in Traditional Chinese Medicine

摘　　要：目的观察清胰汤保留灌肠治疗重症急性胰腺炎(SAP)的疗效和对患者血清C反应蛋白(CRP)水平的影响。方法40例SAP患者随机分为两组,行APACHEⅡ评分并测血清CRP。两组均采用综合治疗,治疗组加用清胰汤保留灌肠治疗。分别测每组患者治疗后第1、3、7日血清CRP水平及APACHEⅡ分值,记录每组患者的平均治愈时间、转手术和死亡例数。结果入院时两组病例的血清CRP和APACHEⅡ评分差异无统计学意义;治疗第1、3、7日治疗组血清CRP水平和APACHEⅡ分值较对照组均明显降低,治疗组平均治愈时间明显缩短,转手术和死亡率明显降低。结论加用清胰汤保留灌肠治疗可显著降低急性胰腺炎患者血清CRP水平,缩短病程,提高疗效。Objective： To observe the effect of Qingyi Decoction retention enema on the levels of C-reactive protein in severe acute pancreatitis （SAP）. Methods： 40 SAP patients were randomly divided into two groups （20 patients each group） and measured C-reactive protein levels in serum and APACHE Ⅱ score on each case. Both groups were treated by conventional therapy. The treatment group was added Qingyi Decoction retention enema. The levels of C-reactive protein in serum and APACHE Ⅱ scores were measured at the 1st, the 3rd and the 7th day of treatment. The average healing time, the number of surgery and the death rate in each group were recorded. Results： The C-reactive protein in serum and the APACHE Ⅱ scores were no significant differences between the two groups on admission. Compared with the control group, the C-reactive protein in serum and the APACHE Ⅱscores of treatment group significantly were reduced at the 1st, the 3rd and the 7th day of treatment, the average healing time was significantly shorter, transfer surgery and mortality rates decreased significantly. Conclusion： The Qingyi Decoction retention enema therapy can significantly reduce C-reactive protein levels, shorten the course and improve efficacy of SAP patients.

关 键 词：重症急性胰腺炎 清胰汤 保留灌肠 C反应蛋白 

分 类 号：R576[医药卫生—消化系统]