肾素瘤的诊断和治疗(附3例报告)  

The diagnosis and treatment of reninoma(report of 3 cases)

作　　者：涂响安[1] 赵亮[1] 梁辉[1] 赵良运[1] 邓立文[1] 王文卫[1] 曾令有[1] 戴宇平[2] 

机构地区：[1]中山大学附属第一医院黄埔院区泌尿外科,广州510700 [2]中山大学附属第一医院泌尿外科,广州510080

出　　处：《现代泌尿外科杂志》2010年第2期93-95,共3页Journal of Modern Urology

摘　　要：目的提高肾素瘤的诊治和治疗水平。方法回顾分析3例肾素瘤患者的临床资料,结合文献复习进行讨论。3例患者均表现有高血压、高肾素和高醛固酮血症。2例临床表现有低血钾。结果2例患者行保留肾单位的肾肿瘤切除术,1例行肾切除术,术后病理示:肾素瘤。3例患者术后血压、血浆肾素、醛固酮和血钾等恢复正常,随访3～12年未见肿瘤复发及高血压再发。结论肾素瘤为罕见的良性肾脏肿瘤,肿瘤根治性切除效果满意,预后良好。Objective To improve the diagnosis and treatment of reninoma. Methods We compared the data of 3 cases of reninoma and reviewed the literature. Results All patients had hypertension and high levels of peripheral serum renin activity and hyperaldosteronism. 2 of them had hypokalemia. Partial nephrectomy was performed in 2 patients and total nephrectomy in 1 patient. Post-operative histopathological study revealed reninoma. The hypertension, peripheral serum renin activity, hyperaldosteronism and hypokalemia returned normal after tumor resection. During a mean follow-up of 84 months （range 36 to 144 months ）, no tumor recurrence and hypertension were documented. Conclusions Reninoma is a benign tumor of kidney, which can be satisfactorily cured with tumor resection.

关 键 词：肾肿瘤 肾素瘤 肾球旁细胞瘤 

分 类 号：R737.1[医药卫生—肿瘤]