丝裂霉素C在LASIK术后角膜上皮植入手术治疗中的应用  

Application of mitomycin C in surgical treatment of epithelial ingrowth after LASIK

作　　者：韩苏宁[1] 陈静[1] 王泳[1] 邓金印[1] 方慧丽[1] 李欣[1] 陈晓娟[1] 龚小雪[1] 朱海萍[1] 

机构地区：[1]广州军区广州总医院眼科,中国广东省广州市510010

出　　处：《国际眼科杂志》2010年第3期579-580,共2页International Eye Science

摘　　要：目的:探讨丝裂霉素C(mitomycin C,MMC)在准分子激光原位角膜磨镶术(laserin situkeratomileusis,LASIK)术后角膜上皮植入手术治疗中应用的临床疗效。方法:在31例31眼LASIK术后角膜上皮植入患者手术治疗中应用0.2g/L MMC,观察术后裸眼视力及角膜瓣愈合情况。结果:术后6mo裸眼视力平均为0.82±0.19,较术前明显提高(P<0.05)。绝大部分患者角膜瓣愈合良好,4例患者角膜瓣边缘部分融解,但中心视力无明显影响。结论:在LASIK术后角膜上皮植入手术治疗中应用0.2g/LMMC可以取得良好的临床疗效。AIM. To observe the clinical effect of using mitomycin C （MMC） during surgical treatment of epithelial ingrowth after laser in situ keratomileusis （LASIK）. METHODS： MMC 0. 2g/L was applied in surgical treatment of epithelial ingrowth after LASIK on 31 patients （31 eyes）. The uncorrected visual acuity and the recovery of corneal flap were observed after surgery.RESULTS： The uncorrected visual acuity increased after surgery （P〈 0.05） and was 0.82±0.19 6 months postoperatively. Majority of corneal flaps recovered well. Fringe of the flap melted in 4 eyes, but central visual acuity had no effect.CONCLUSION： Excellent outcome was found in the surgical treatment of epithelial ingrowth after LASIK by using 0.29/L MMC.

关 键 词：准分子激光原位角膜磨镶术 上皮植入 丝裂霉素C 

分 类 号：R779.63[医药卫生—眼科]