修复汤含漱内服治疗急性放射性口腔炎的临床研究  

Clinical study on the treatment of acute radioactive stomatitis with Xiufu Decoction

作　　者：王丽[1] 王天松[2] 邢玉梅[3] 

机构地区：[1]山东省威海市文登中心医院儿科,文登264400 [2]山东省威海市文登中心医院院容科 [3]山东省威海市文登中心医院肿瘤科

出　　处：《国际中医中药杂志》2010年第2期164-165,共2页International Journal of Traditional Chinese Medicine

摘　　要：目的 探讨修复汤含漱内服治疗急性放射性口腔炎的临床疗效。方法将108例肿瘤放疗患者分为两组，治疗组56例和对照组52例，治疗组采用修复汤含漱内服，连用15d；对照组含化制霉菌素片，3次／d，连用15d。结果两组患者用药后疼痛缓解时间、霉菌性口腔炎患者控制情况、生活质量及综合疗效比较，差异均有统计学意义（p均〈0．01或〈0．05）。治疗组56例均顺利完成放疗计划；对照组52例其中5例因口腔溃疡严重影响进食暂停放疗。结论修复汤可增强免疫、修复创面、缓解疼痛、改善饮食和睡眠等提高患者的生活质量，且安全、无毒副作用。Objective To explore the clinical effects of treating acute radioactive stomatitis with Xiufu Decoction by mouth-washing and oral-taking. Methods All 108 cancer patients were recruited into a treatment group （n=56） and a control group （n=52）. The treatment group was treated with Xiufu Decoction for 15 days, and the control group was treated with Nystatin tabletsfor 15 days, 3 times/day. Results There was significant difference between the two groups in odynolysis time, the control of mycotic stomatitis, life condition, and overall effects （P〈0.01 or P〈0.05）. All patients in the treatment group completed the whole course of radiotherapy; while 5 patients in the control group suspended the radiotherapy due to serious mouth ulcer. Conclusion Xiufu Decoction has the functions of enhancing immunity, fixing wound surface, relieving pain, improving diet and sleep, raising life quality, and safeguarding the process of radiation therapy, besides the decoction is safe and without toxic effect.

关 键 词：急性放射性口腔炎 修复汤 含漱内服 

分 类 号：R730[医药卫生—肿瘤]