高-低氧放疗在晚期腹盆腔肿瘤治疗中的应用及价值  

Value of carbogen plus low concentration oxygen radiotherapy in patients with advanced cancer in abdomen or pelvis

作　　者：刘山[1] 安永恒[2] 丁兆军[1] 迟玉华[1] 

机构地区：[1]日照市人民医院肿瘤科,山东日照276800 [2]青岛大学医学院附属医院肿瘤治疗中心,266003

出　　处：《临床肿瘤学杂志》2010年第3期257-259,共3页Chinese Clinical Oncology

摘　　要：目的探讨高-低氧放疗在晚期腹盆腔肿瘤姑息治疗中的价值。方法60例晚期腹盆腔肿瘤患者分为高-低氧放疗组和普通放疗组,每组30例,比较放疗后两组的副反应及生存质量、生存时间。结果放疗后高-低氧组白细胞减少较普通组轻(P<0.05),两组血红蛋白和血小板减少无明显差异(P>0.05);急性腹泻发生率高-低氧组低于普通组(P<0.05);生存质量改善及生存时间,高-低氧组优于普通组(P<0.05)。结论在晚期腹盆腔肿瘤的姑息治疗中,高-低氧放疗优于普通放疗。Objective To study the value of carbogen plus low concentration oxygen radiotherapy（CPLCOR） in patients with advanced cancer in abdomen or pelvis.Methods Sixty patients with advanced cancer in abdomen or pelvis were assigned to two groups equally at random.One group took up carbogen plus low concentration oxygen radiotherapy and the controller took up traditional radiotherapy（TR）.The side effects,survival and quality of life were compared.Results The degree of WBC descent in CPLCOR group was less than the control group（P〈0.05）and there was no statistical difference in descent of HGB and PLT.Acute diarrhea rate after radiation of CPLCOR group was lower than that of TR group.The group that took up carbogen plus low concentration oxygen radiotherapy was superior to the controller on survival span and quality of life（P〈0.05）.Conclusion In the palliative therapy of advanced abdominal or pelvic cancer,carbogen plus low concentration oxygen radiotherapy was superior to traditional radiotherapy.

关 键 词：放射治疗 高-低氧 姑息性 腹盆腔肿瘤 

分 类 号：R730.55[医药卫生—肿瘤]