鼻咽癌放射性脑病147例MR表现特点分析  

MR features of radiation encephalopathy in 147 patients with nasopharyngeal carcinoma

作　　者：卢秋霞[1] 卫光宇[1] 陈露斯[1] 张宁[1] 梁少强[1] 卢瑞梁[2] 

机构地区：[1]佛山市第一人民医院放疗科,广东佛山528000 [2]佛山市第一人民医院医学影像科,广东佛山528000

出　　处：《中华肿瘤防治杂志》2010年第2期122-125,共4页Chinese Journal of Cancer Prevention and Treatment

摘　　要：目的:探讨鼻咽癌放射性脑病(REP)147例的MR表现特征。方法:回顾性分析147例鼻咽癌REP患者MR常规加增强扫描的影像学特点。结果:147例鼻咽癌REP中颞叶损伤122例(83.0%),脑干损伤13例(8.8%),颞叶+脑干混合损伤12例(8.2%),共检出224侧颞叶及25例脑干REP病灶。颞叶型REP:形态多样,水肿(96.9%)及强化(94.7%)常见,30.8%有占位效应。脑干型REP:多数为单发(22/25),体积较小(≤2.0 cm),多均匀强化,水肿及占位效应较轻,动态观察可见病灶消失(7/25),明显缩小(4/25)。结论:鼻咽癌REP的MR表现具有特征性及动态变化的特点。颞叶仅1侧病灶消失;脑干REP经治后部分病灶可缩小或消失,并伴有脑干萎缩。OBJECTIVE：To detect the characteristics of magnetic resonance（MR） imaging of radiation encephalopathy（REP） in patients with nasopharyngeal carcinoma（NPC）.METHODS：The characteristics of MR scanned by routine and enhancement means were analyzed retrospectively in 147 postradiotherapeutic patients with NPC.RESULTS：Among them,temporal lobe injury,brainstem injury both injury had appeared in 122（83.0%）,13（8.8%） and 12（8.2%） patients,respectively.Totally there were 224 sides of temporal lobe injury and 25 cases of brainstem injury which were defined to REP.The MR appearances of temporal-lobe-type REPs were described as edema（96.9%） and enhancement（94.7%）,and the space-occupied effect was observed in 30.8% of them.The brainstem-type REPs were mostly solo（22/25）,small（≤2.0 cm） lesions,and enhanced well-distributed.Edema and space-occupied effect were slight among them.The injury lesions disappeared in 7 patients,and became weak obviously in 4 patients in the period of observation.CONCLUSIONS：The MR appearance of in patients with NPC REP is characteristics and kept changing.Only one patient with temporal lobe injury has lesion disappeared,and the lesions in brainstem have more often disappeared or shrieked after the treatment,but they sometime accompanied with brainstem atrophy.

关 键 词：鼻咽肿瘤/放射疗法 放射性脑病 磁共振成像 

分 类 号：R739.63[医药卫生—肿瘤]