儿童癫痫发作间期SPECT高灌注灶与EEG致痫区之间的关系  

Correlation between SPECT cerebral hypertrnsfusion focus and EEG epileptogenic zone in children with epilepsy interictal

作　　者：王为民[1] 王文婷[1] 

机构地区：[1]兰州大学第二医院神经内科／癫痫中心,甘肃省癫痫治疗基地,甘肃兰州730030

出　　处：《癫痫与神经电生理学杂志》2010年第1期18-20,共3页Journal of Epileptology and Electroneurophysiology(China)

摘　　要：目的：观察早期儿童癫痫病例单光子发射计算机层体摄影（SPECT）高灌注灶与脑电图（EEG）致痫灶之间的相关性。方法：对30例儿童癫痫SPECT高灌注显像病例进行同步录像脑电图（V-EEG）进行12h长程监测，分析这两种方法结果的相关性。结果：发作间期SPECT显像高灌注灶者29例（97％），高低灌注灶者1例（3％）；单灶者13例（43％）13个灶，多灶者17例（57％）41个灶，共54个灶。EEG30例均异常，有痫样放电者29例（97％），其中局限性异常18例（60％），广泛性异常11例（37％），另有慢波异常者1例。SPECT高灌注灶与EEG的致痢灶相符者7例（23％），相近者7例（23％），不相符者16例（54％）。结论：早期儿童癫痫病例SPECT的高灌注灶与EEG的致痫灶的相关性较低。Objective：To explore the correlation between cerebrac hypertransfusion focus of SPECT and epileptogenic zones of EEG in children with epilepsy interictal. Methods- Trirty epileptic children with eerebrac hypertransfusion focus on SEPCT were examined by long-term V-EEG monitoring for 12 hours. And the position of the hypertransfusion focus as compared with that of epileptogenic zones on EEG. Resuits： Through interictal SPECT perfusion imaging, hypertransfusion showed in 29 patients （97M） ,hyperrhypotrasfusion：in one （3%） ;Including single loci in 13 cases, multifocux in 17 cases （47 focus all together）. EEG abnormality in all the 30 patients,epileptiform discharge in 29 cases （97%） ,including focal discharge in 18 cases and widespread in 11 cases. CT/MRI abnormality in 4 ases（13%）. In the association of SPECT hypertransfusion focus and EEG epileptiform discharge zones, the conforimity type and similarity type took up 7 cases（23% ） respectively, the dispersion type in 12 cases , the diffuse type in 3 cases,and no epileptiform dischange type in one. Conclusions： There is rather low correlation between hypertransfUSion focus of SPECT and epileptogenic zones of EEG in the children with epilepsy interietat,and most of hypertransfusion focus can not replace epileptogenic zones . The conformity is 23% in the both focus and zones.

关 键 词：癫痫 单光子发射计算机层体摄影(SPECT) 高灌注灶 脑电图(EEG) 致痫区 

分 类 号：R742.1[医药卫生—神经病学与精神病学] R814.42[医药卫生—临床医学]