锌及复合微量营养素的营养干预对学龄前儿童认知功能的影响  

Influence of Zinc and Micronutrient on Cognitive Function in Preschool Children

作　　者：糜漫天[1] 杨家驹[1] 石元刚[1] 杨镇洲[1] 韦娜[1] 张乾勇[1] 黄国荣[1] 万志红[1] 陈学存[1] 

机构地区：[1]第三军医大学预防医学系

出　　处：《微量元素与健康研究》1998年第4期29-31,共3页Studies of Trace Elements and Health

基　　金：国际铅;锌基金会;Thrasher基金会资助

摘　　要：相同年龄段（６～７岁）学龄前儿童２８０名，男、女各半，分为锌组（Ｚｎ组）、锌加复合微量营养素组（ＺｎＭ组）和单纯补充微量营养素组（Ｍ组），每组８０人，另外４０名儿童为对照组，采用双盲法进行营养干预实验，实验周期为１０周。结果显示，重庆市城区学龄前儿童近８０％处于边缘性锌缺乏状态，一半以上儿童血铅超过０．４８３μｍｏｌ／Ｌ的安全标准，经过１０周营养干预后，发现每日补充１６ｍｇ锌的同时再添加多种复合微量营养素能有效增加儿童血锌含量、降低血铅水平，同时明显增强儿童的认知功能，而单纯补锌效果并不理想。本研究儿童认知功能的改善可能与体内良好的锌营养状况、铅负荷减少有关。Objective:To investigate the effects of Zinc and micronutrient supplementation on cognitive function in preschool children.Methods:A 10 week double-blind controlled trial was carried out in 280 preschool children,6 to 7 year old (half boys and half girls).Treatments were 16mg zinc alone(Zn),16mg zinc with micronutrients(ZnM),and micronutrients alone.Result:near 80% preschool children living in Chongqing downtown were in marginal zinc deficiency ,the blood lead content of over half of subjects exceeded 0.483 μmol/L upper limit(secure level).After 10 Week untritional intervention,serum Zine concentration increased,blood lead content decreased and the neuropsychological performance(Cognitive function)was improved,especially in those children who received Zinc and micronutriente supplementation simultaneously Conclusion:zinc and other micronutrient repletion can improve the neuropsycholocial performance of children.

关 键 词：锌 微量营养素 学龄前儿童 认知功能 

分 类 号：R175[医药卫生—妇幼卫生保健] R153.2[医药卫生—公共卫生与预防医学]