Wistar大鼠牙周炎动物模型口腔菌群及病理观察  

OBSERVATION ON ORAL CAVITY FLORA AND PATHOLOGY OF ANIMAL TEST MODELS WITH PERIODONTIUM FOR WISTAR RATS

作　　者：马晟利[1] 王建平[1] 孙庆顺[1] 吴力鹏 李生[1] 刘丽娟[1] 

机构地区：[1]佳木斯医学院附属口腔医院

出　　处：《中国微生态学杂志》1998年第5期270-272,共3页Chinese Journal of Microecology

摘　　要：本文以Ｗｉｓｔａｒ大鼠为实验对象，以激素＋剥离的方法成功地制造了类似人类牙周炎动物模型。纵观牙周炎全过程，菌群失调贯穿自始至终，菌群失调持续一定时间后才出现病理改变，证明菌群失调是导致牙周炎的因素之一。Animal test models with periodontitis similor to humen were producted by applying hormone on its whole-body and local strip for Wista rats.Periodontitis was accompanied with flora imbalance from the begining to the end.Pathologic changes occurred after oral cavity flora imbalance lasted for a pariod of time.The study saggested:Flora imbalance is one of the factors that lead to periodontitis.

关 键 词：牙周炎 动物模型 菌群失调 病理 

分 类 号：R781.42[医药卫生—口腔医学]