120例难治性抑郁症中医征候分析  

The Analysis of 120 Treat-resistant Depression Patients's TCM Patterns

作　　者：刘杰[1] 贾竑晓[1] 邹忆怀[2] 王建琴[1] 

机构地区：[1]首都医科大学附属北京安定医院,北京100088 [2]北京中医药大学附属东直门医院,北京100700

出　　处：《中华中医药学刊》2010年第4期723-725,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：北京市中医医药科技发展基金资助项目(JJ2005-16)

摘　　要：目的:探讨难治性抑郁症的中医证候特点及辨证分型规律。方法:通过对120例难治性抑郁症患者的临床流行病学调查,采集病史、症状、舌、脉等基本信息,以频数分析、聚类分析、主成分分析的方法分析难治性抑郁症的证候分布规律及证候特点。结果:难治性抑郁症常见症状共36种,出现频率较高的有:忧愁善感、烦躁、神疲乏力、兴趣索然、食欲下降、倦卧少动等,常见辨证分型分为5类:肝郁脾虚、气郁化火、脾肾阳虚、肝郁痰阻、肝郁血瘀。结论:难治性抑郁症与普通抑郁症在证候特点有不同之处。Objective ： To study the general law of typing and TCM Patterns for treatment - resistant depression accord- ing to syndrome differentiation. Methods：Through the epidemiological investigation, by way of epidemiological investiga- tion, We collected the symptoms, physical signs, tongue demonstrations and pulse tracings in 120 patients with treatment -resistant depression, using Frequency and cluster analysis,also with principal component analysis as research diserimi- nant for TCM Patterns. Results： There are 36 species symptoms usually seen in treatment - resistant depression. The most common of them are ： incessant worries and miseries , restlessness, fatigue, lose of interest, hebetude, dysorexia, drows- iness and hypokinesia and so on. According to syndrome types, TCM Patterns devided into five category as ： stagnation of liver - QI with deficiency of the spleen , stagnated QI transforming into fire, asdthenic splenonephro - yang , hepatic stag- nation and retention of phlegm, hepatic stagnation and blood stasis. Cortclusion ： Treatment - resistant depression is different in features of TCM Patterns to common depression.

关 键 词：难治性抑郁症 中医证候 聚类分析 

分 类 号：R749.41[医药卫生—神经病学与精神病学]