五灵脂石油醚部分化学成分的气相色谱-质谱联用分析  

GC/MS analysis of chemical constituents of P-ether extract from trogopterus xanthippes milne-edwards

作　　者：朱翔宇[1] 杨莲菊[2] 李春[2] 

机构地区：[1]西南交通大学生命科学与工程学院,成都610031 [2]中国中医科学院中药研究所,北京100700

出　　处：《中国实验方剂学杂志》2010年第4期18-20,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家自然科学基金(30873382)

摘　　要：目的:研究五灵脂石油醚部分的化学成分。方法:乙醇热回流提取五灵脂药材,提取液浓缩后拌硅胶经硅胶柱色谱,依次用石油醚、乙酸乙酯、正丁醇洗脱,回收溶剂得石油醚、乙酸乙酯、正丁醇部分。用气相色谱-质谱(GC/MS)联用技术对石油醚部分化学成分进行分离鉴定,用面积归一化法确定各成分的相对含量。结果:共鉴定21个化合物,均为首次从五灵脂中分离鉴定出。结论:五灵脂石油醚部分的主要成分为正四十一烷醇(21.72%)、香紫苏醇(14.08%)、棕榈酸(9.11%)等,其中醇类化合物占总量的40%以上。Objective：To study on the chemical constituents of the petroleum ether extract of Trogopterus xanthippes Milne-Edwards.Method： The ethanol extract of Trogopterus xanthippes Milne-Edwards underwent silica gel chromatography and was eluted by petroleum ether,ethyl acrylate and n-buthanol in turn.The composition of petroleum ether part was analysed and identified by GC /MS and the relative content of composition was calculated by area normalization method.Result： 21 components were identified,and all of them were first discovered from the Excreta of Trogopterus xanthippes Milne-Edwards.Conclusion： Hentetracontan-1-ol（21.72%）,sclareol（14.08%） and n-hexadecanoic acid（9.11%） were the main chemical compositions of the petroleum ether extract,and the content of alcohol components was more than 40% in total.

关 键 词：五灵脂 化学成分 气相色谱-质谱联用 

分 类 号：R284.1[医药卫生—中药学]