术后限制补液策略对不同体重指数结直肠癌患者的临床效果研究  

Clinical Effects of Postoperative Restrict Rehydration on Different Body Mass Index of Patients with Colorectal Cancer

作　　者：肖凌[1,2,3] 王浩洋[1,2,4] 余曦[1,2,4] 汪晓东[1,2] 李立[1,2] 

机构地区：[1]四川大学华西医院胃肠外科中心,成都610041 [2]四川大学华西医院MCQ团队,成都610041 [3]四川大学口腔医学院,成都610041 [4]四川大学华西临床医学院,成都610041

出　　处：《中国普外基础与临床杂志》2010年第3期289-293,共5页Chinese Journal of Bases and Clinics In General Surgery

基　　金：四川省卫生厅科研项目(项目编号:090353)~~

摘　　要：目的探讨在快速流程模式下不同体重指数(BMI)患者液体限制策略下的临床效果。方法回顾性研究2008年1月至2009年1月期间四川大学华西医院结直肠外科专业组收治的354例结直肠癌患者的病例资料,分析术后不同补液方式下不同BMI患者术后康复情况。结果从术后康复指标看,限制补液组的术后首次排气、排便及下床活动时间均早于常规补液组(P<0.05),且术后住院时间也更短(P<0.05)。常规补液组及限制补液组中的偏瘦组、正常组及超重组之间的术后康复情况的差异均无统计学意义(P>0.05);从术后并发症的发生率看,限制补液组的肺部感染、吻合口漏、肠梗阻和伤口裂开的发生率均低于常规补液组(P<0.05);常规补液组中的超重组的吻合口漏和伤口裂开的发生率高于偏瘦组和正常组(P<0.05)。限制补液组中的3个亚组术后并发症发生率的差异无统计学意义(P>0.05)。结论术后限制补液策略在超重结直肠癌患者的术后康复中效果良好,能促进其术后早期康复。Objective To explore the clinical effects of postoperative restrict rehydration on different body mass index（BMI）of patients with colorectal cancer.Methods From January 2008 to January 2009,the patients diagnosed definitely as colorectal cancer were analyzed retrospectively.The postoperative early rehabilitations were studied and compared in different fluid therapy with different BMI（underweight group,normal group,overweight group）.Results The first defecation time,aerofluxus time and ambulation time of the fluid restriction group were significantly earlier than those of the tradition therapy group（P〈0.05）,and postoperative in-hospital time was also less（P〈0.05）.However,the differences of early postoperative rehabilitation among underweight group,normal group and overweight group in the tradition therapy group and fluid restriction group had no statistical significance（P〉0.05）.The complications such as pulmonary infection,anastomotic leakage,intestinal obstruction and wound dehiscence in the fluid restriction group were significantly lower than those in the tradition therapy group（P〈0.05）.In the tradition therapy group,the incidences of anastomotic leakage and wound dehiscence in overweight group were significantly higher than those in the underweight and normal group（P〈0.05）.The rate of postoperative complications among underweight group,normal group and overweight group in the fluid restriction group had no statistical significance（P〉0.05）.Conclusion Postoperative restrict rehydration for overweight colorectal cancer patients has a good clinical effect,which can promote the early postoperative rehabilitation.

关 键 词：快速流程 结直肠肿瘤 体重指数 限制补液 

分 类 号：R735.3[医药卫生—肿瘤]