淋巴示踪剂在结直肠癌外科的研究进展  

Advances of Lymphatic Tracer in Colorectal Cancer Surgery

作　　者：尹源[1] 汪晓东[2] 吕东昊[1] 李立[2] 

机构地区：[1]四川大学华西临床医学院/华西医院,成都610041 [2]四川大学华西医院胃肠外科中心,成都610041

出　　处：《中国普外基础与临床杂志》2010年第3期306-308,共3页Chinese Journal of Bases and Clinics In General Surgery

摘　　要：目的探讨淋巴示踪剂在结直肠癌外科诊治中的应用价值。方法复习有关淋巴示踪剂在结直肠癌外科中应用的文献。结果应用淋巴示踪剂能够提高结直肠癌手术中淋巴结检出量,并有助于在术中定位并检取前哨淋巴结,从而提高病理分期的准确性,帮助医生制定最恰当的治疗方案。此外,淋巴示踪剂在混合化疗药物进行淋巴靶向化疗方面具有较大的潜力,有望成为改善结直肠癌患者预后的有效手段。结论淋巴示踪剂为结直肠癌的外科诊疗提供了很大的帮助,但其更广泛的应用有赖于更多临床研究的探索。Objective To investigate the value of lymphatic tracer on surgery for colorectal cancer.Methods Literatures about lymphatic tracer and lymphatic mapping in colorectal cancer were reviewed.Results Lymphatic mapping technique was helpful to increase the numbers of lymph node harvested,to identify sentinel lymph node,thereby increased the accuracy of pathological staging.Besides,lymphatic tracer had great potential uses in lymph nodes targeted chemotherapy during surgery,which might improve prognosis in colorectal cancer patients.Conclusions The lymphatic tracer has been powerful in diagnosis and treatment for colorectal cancer.The more extensive and more profound application of lymphatic mapping depend on more clinical study.

关 键 词：结直肠癌 淋巴示踪剂 淋巴显影 外科手术 淋巴靶向化疗 

分 类 号：R735.3[医药卫生—肿瘤]