经支气管镜微波治疗联合瘤体注射治疗中央型肺癌疗效探讨  

The Treatment Effects of Microwave Therapy Combined with Intratumoral Injection on Central lung Cancer

作　　者：宋卓[1] 刘旭之[1] 刘琰[1] 

机构地区：[1]齐齐哈尔医学院附属第三医院呼吸内科,黑龙江齐齐哈尔161000

出　　处：《慢性病学杂志》2010年第4期296-298,共3页Chronic Pathematology Journal

摘　　要：目的:探讨支气管内微波治疗联合局部瘤体注射治疗中央型肺癌的疗效。方法:将2006-02/2009-05齐齐哈尔医学院附属第三医院呼吸内科收治的38例晚期中央型肺癌患者随机分为治疗组和对照组。治疗组20例采用支气管内微波治疗并局部瘤体注药,对照组18例仅进行局部瘤体注药。结果:20例治疗组平均微波治疗联合药物注射3.5次,症状改善率90%,KPS评分提高率95%,支气管镜下病灶好转率80%,胸部CT肺不张或阻塞性肺炎好转率75%,与对照组相比差异有统计学意义(P<0.05)。结论:晚期中央型肺癌患者采用支气管内微波治疗联合局部瘤体注射疗法,能有效的缓解呼吸困难,解除阻塞,提高生活质量,且优于单纯局部药物注射疗法。Objective：To discuss the treatment effects of microwave therapy combined with intratumoral injection on central lung cancer.Methods：From February 2005 to May 2008,38 patients with advanced central lung cancer were divided randomly into therapy group and control group.20 patients in the therapy group were treated with microwave therapy combined with intratumoral drug injection,while 18 patients in the control were only treated with intratumoral drug injection.Results：After average 3.5 times treatment in the therapy group,Symptom improvement rate was 90%,KPS score increased by 95%,and lesions improved by 80%,the remission rate of pulmonary atelectasis or obstructive pneumonia was 75%.Compared with the control group,the differences were statistically significant.Conclusions：Microwave therapy combined with intratumoral injection can effectively alleviate dyspnea,relieve obstruction,and improve the quality of life for the patients with advanced central lung cancer,which is better than the intratumoral injection alone.

关 键 词：肺肿瘤/治疗 微波/治疗应用 抗肿瘤药/治疗应用 

分 类 号：R734.2[医药卫生—肿瘤]